Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
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Amino-terminal determinants of U-type inactivation of voltage-gated K+ channelsThe KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interactionMutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome.Structural insight into KCNQ (Kv7) channel assembly and channelopathyIon channel gene expression in the inner earIsolation from cochlea of a novel human intronless gene with predominant fetal expressionMolecular phylogeny of the kelch-repeat superfamily reveals an expansion of BTB/kelch proteins in animalsSequence and structural analysis of BTB domain proteinsComputational identification of residues that modulate voltage sensitivity of voltage-gated potassium channels.Zinc as Allosteric Ion Channel Modulator: Ionotropic Receptors as MetalloproteinsDetermining the basis of channel-tetramerization specificity by x-ray crystallography and a sequence-comparison algorithm: Family values (FamVal)X-ray Crystal Structure of a TRPM Assembly Domain Reveals an Antiparallel Four-stranded Coiled-coilPentameric Assembly of Potassium Channel Tetramerization Domain-Containing Protein 51.2 Å X-ray structure of the renal potassium channel Kv1.3 T1 domainCa(2+) and ion channels in hypoxia-mediated pulmonary hypertensionThe Roles of N- and C-terminal determinants in the activation of the Kv2.1 potassium channelENaC subunit-subunit interactions and inhibition by syntaxin 1AKinesin I transports tetramerized Kv3 channels through the axon initial segment via direct bindingMutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouseFormation of heteromeric Kv2 channels in mammalian brain neuronsActivation of conventional kinesin motors in clusters by Shaw voltage-gated K+ channels.Robust recognition of zinc binding sites in proteins.The desensitization gating of the MthK K+ channel is governed by its cytoplasmic amino terminus.Conserved negative charges in the N-terminal tetramerization domain mediate efficient assembly of Kv2.1 and Kv2.1/Kv6.4 channels.Zn2+ activates large conductance Ca2+-activated K+ channel via an intracellular domain.Tetramerization domain mutations in KCNA5 affect channel kinetics and cause abnormal trafficking patterns.Carbon monoxide--physiology, detection and controlled release.Functional rescue of Kv4.3 channel tetramerization mutants by KChIP4a.Controlling potassium channel activities: Interplay between the membrane and intracellular factors.The tetramerization domain potentiates Kv4 channel function by suppressing closed-state inactivation.Gating of amiloride-sensitive Na(+) channels: subunit-subunit interactions and inhibition by the cystic fibrosis transmembrane conductance regulator.Protein partners of KCTD proteins provide insights about their functional roles in cell differentiation and vertebrate development.Coiled coils direct assembly of a cold-activated TRP channel.An artificial tetramerization domain restores efficient assembly of functional Shaker channels lacking T1The subfamily-specific interaction between Kv2.1 and Kv6.4 subunits is determined by interactions between the N- and C-termini.Cullin3-BTB interface: a novel target for stapled peptidesPositive Allosteric Modulation of Kv Channels by Sevoflurane: Insights into the Structural Basis of Inhaled Anesthetic ActionInterdomain cytoplasmic interactions govern the intracellular trafficking, gating, and modulation of the Kv2.1 channel.Molecular and Functional Differences between Heart mKv1.7 Channel Isoforms.
P2860
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P2860
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
@ast
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
@en
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
@nl
type
label
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
@ast
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
@en
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
@nl
prefLabel
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
@ast
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
@en
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
@nl
P2093
P3181
P356
P1476
Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels
@en
P2093
P J Pfaffinger
P3181
P356
10.1038/4911
P577
1999-01-01T00:00:00Z