Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
about
Systems pharmacology: network analysis to identify multiscale mechanisms of drug actionMammalian target of rapamycin inhibitor-associated stomatitisPharmacogenetic biomarkers for the prediction of response to antiangiogenic treatmentIndividualising treatment choices in a crowded treatment algorithmCIViC databaseInfluence of Tyrosine Kinase Inhibitors on Hypertension and Nephrotoxicity in Metastatic Renal Cell Cancer PatientsEarly sorafenib-induced toxicity is associated with drug exposure and UGTIA9 genetic polymorphism in patients with solid tumors: a preliminary studySunitinib as a second-line therapy for advanced GISTs after failure of imatinib: relationship between efficacy and tumor genotype in Korean patients.Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy.Understanding, recognizing, and managing toxicities of targeted anticancer therapies.Pharmacogenetic determinants associated with sunitinib-induced toxicity and ethnic difference in Korean metastatic renal cell carcinoma patients.Sunitinib in metastatic renal cell carcinoma: an ethnic Asian subpopulation analysis for safety and efficacy.Role of the lean body mass and of pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of sunitinib in cancer patients.Polymorphisms in SLCO1B3 and NR1I2 as genetic determinants of hematotoxicity of carboplatin and paclitaxel combination.Pharmacokinetically guided sunitinib dosing: a feasibility study in patients with advanced solid tumours.Identifying novel genes and biological processes relevant to the development of cancer therapy-induced mucositis: An informative gene network analysis.Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib.Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action?A phase I study of sunitinib plus capecitabine in patients with advanced solid tumorsA phase I dose-escalation study to evaluate safety and tolerability of sorafenib combined with sirolimus in patients with advanced solid cancer.Polymorphisms in endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) predict sunitinib-induced hypertension.Tyrosine kinase inhibitors: Multi-targeted or single-targeted?Current progress in pharmacogenetics.Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.A case of metastatic renal cell carcinoma and bile duct carcinoma treated with a combination of sunitinib and gemcitabine.Oral adverse events associated with tyrosine kinase and mammalian target of rapamycin inhibitors in renal cell carcinoma: a structured literature review.Interaction of innovative small molecule drugs used for cancer therapy with drug transporters.Association of ABCB1 and FLT3 Polymorphisms with Toxicities and Survival in Asian Patients Receiving Sunitinib for Renal Cell Carcinoma.Randomised phase II trial of docetaxel and sunitinib in patients with metastatic gastric cancer who were previously treated with fluoropyrimidine and platinum.Efflux transporter variants as predictors of drug toxicity in lung cancer patients: systematic review and meta-analysis.Variability of sorafenib toxicity and exposure over time: a pharmacokinetic/pharmacodynamic analysisAssociation of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma.Biomarkers for tyrosine kinase inhibitors in renal cell cancer.The influence of genetic variants of sorafenib on clinical outcomes and toxic effects in patients with advanced renal cell carcinoma.Everolimus pharmacokinetics and its exposure-toxicity relationship in patients with thyroid cancer.Methylomes of renal cell lines and tumors or metastases differ significantly with impact on pharmacogenesBuccodental side effects of sunitinib in patients with metastatic renal cell carcinomaMeta-analysis on the association of VEGFR1 genetic variants with sunitinib outcome in metastatic renal cell carcinoma patients.Oral mucositis: the new paradigms.Drug transport by breast cancer resistance protein.
P2860
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P2860
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
@ast
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
@en
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
@nl
type
label
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
@ast
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
@en
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
@nl
prefLabel
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
@ast
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
@en
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
@nl
P2093
P3181
P356
P1476
Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.
@en
P2093
An K L Reyners
Astrid A van der Veldt
Epie Boven
Hans Gelderblom
John B Haanen
Judith A M Wessels
Karel Eechoute
Nielka P van Erp
Renée F Baak-Pablo
Ron H J Mathijssen
P304
P3181
P356
10.1200/JCO.2008.21.7679
P407
P577
2009-09-10T00:00:00Z