Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia. - Wikidata - awgldk - TriplyDB

Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.

Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.

http://www.wikidata.org/entity/Q27853333

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CIViC database The shrinking role of chemotherapy in the treatment of chronic lymphocytic leukemia.Molecular Testing of Lymphoproliferative Disorders: Current Status and Perspectives.MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer.Extensive next-generation sequencing analysis in chronic lymphocytic leukemia at diagnosis: clinical and biological correlations Recurrent somatic mutations affecting B-cell receptor signaling pathway genes in follicular lymphoma.Non-coding NOTCH1 mutations in chronic lymphocytic leukemia; their clinical impact in the UK CLL4 trial.Karyotypic complexity rather than chromosome 8 abnormalities aggravates the outcome of chronic lymphocytic leukemia patients with TP53 aberrations Droplet digital PCR analysis of NOTCH1 gene mutations in chronic lymphocytic leukemia Cell Dispersal Influences Tumor Heterogeneity and Introduces a Bias in NGS Data Interpretation.Genetic landscape and deregulated pathways in B-cell lymphoid malignancies.Learning from the failures of drug discovery in B-cell non-Hodgkin lymphomas and perspectives for the future: chronic lymphocytic leukemia and diffuse large B-cell lymphoma as two ends of a spectrum in drug development.Klhl6 Deficiency Impairs Transitional B Cell Survival and Differentiation.Turning the tide in myelodysplastic/myeloproliferative neoplasms.ASIC1 promotes differentiation of neuroblastoma by negatively regulating Notch signaling pathway.Mutations in NOTCH1 PEST-domain orchestrate CCL19-driven homing of Chronic Lymphocytic Leukemia cells by modulating the tumor suppressor gene DUSP22.Lymphoma classification update: B-cell non-Hodgkin lymphomas.Predictive and prognostic biomarkers in the era of new targeted therapies for chronic lymphocytic leukemia.Chronic lymphocytic leukemia and small lymphocytic lymphoma: two faces of the same disease.Splicing factor gene mutations in hematologic malignancies.Chronic lymphocytic leukaemia genomics and the precision medicine era.EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.CD49d prevails over the novel recurrent mutations as independent prognosticator of overall survival in chronic lymphocytic leukemia.Comprehensive analyses of somatic TP53 mutation in tumors with variable mutant allele frequency.Survival of Del17p CLL Depends on Genomic Complexity and Somatic Mutation.SF3B1 mutation is a prognostic factor in chronic lymphocytic leukemia: a meta-analysis.Next-generation sequencing in chronic lymphocytic leukemia: recent findings and new horizons.Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia.Barcelona conference on epigenetics and cancer 2016 - beyond cancer genomes.NOTCH1 mutations are associated with high CD49d expression in chronic lymphocytic leukemia: link between the NOTCH1 and the NF-κB pathways.NOTCH1 mutational status in chronic lymphocytic leukaemia: clinical relevance of subclonal mutations and mutation types.Extended follow-up and impact of high-risk prognostic factors from the phase 3 RESONATE study in patients with previously treated CLL/SLL.Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia.Clonal evolution in leukemia.Management of high risk chronic lymphocytic leukaemia (CLL) patients in Australia.ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation.Telomere shortening, TP53 mutations and deletions in chronic lymphocytic leukemia result in increased chromosomal instability and breakpoint clustering in heterochromatic regions.TP53 mutations are early events in chronic lymphocytic leukemia disease progression and precede evolution to complex karyotypes.NOTCH1 mutation and its prognostic significance in Chinese chronic lymphocytic leukemia: a retrospective study of 317 cases.What Does This Mutation Mean? The Tools and Pitfalls of Variant Interpretation in Lymphoid Malignancies.

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Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.

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2016 nî lūn-bûn

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2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2016 թվականի ապրիլին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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Clinical impact of clonal and ...... chronic lymphocytic leukemia.

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Clinical impact of clonal and ...... chronic lymphocytic leukemia.

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Clinical impact of clonal and ...... chronic lymphocytic leukemia.

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Clinical impact of clonal and ...... chronic lymphocytic leukemia.

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Clinical impact of clonal and ...... chronic lymphocytic leukemia.

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Clinical impact of clonal and ...... n chronic lymphocytic leukemia

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Armando López-Guillermo

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Ceri Oldreive

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Cristina Royo

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Helena Suárez-Cisneros

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Magda Pinyol

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Marcos González

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P2860

International network of cancer genome projects.

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

Fast and accurate short read alignment with Burrows-Wheeler transform

Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution

Clonal evolution in hematological malignancies and therapeutic implications

The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial.

Recurrent mutations refine prognosis in chronic lymphocytic leukemia.

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

The Sequence Alignment/Map format and SAMtools

Genomic and epigenomic heterogeneity in chronic lymphocytic leukemia

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17

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127

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Carlos López Otín

Itziar Salaverria

Miguel Alcoceba

Maria José Terol

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2016-02-02T00:00:00Z

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26837699

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