CDK inhibitors: positive and negative regulators of G1-phase progression
about
Identification of druggable cancer driver genes amplified across TCGA datasetsGPR158, an orphan member of G protein-coupled receptor Family C: glucocorticoid-stimulated expression and novel nuclear roleAttenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance.Protein kinase C signaling and cell cycle regulationThe retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycleGene expression profiling of monkeypox virus-infected cells reveals novel interfaces for host-virus interactionsCentrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapyBinding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2Increased p21 expression and complex formation with cyclin E/CDK2 in retinoid-induced pre-B lymphoma cell apoptosisInduction of human beta-cell proliferation and engraftment using a single G1/S regulatory molecule, cdk6p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signalingThe cell cycle regulator p27Kip1 interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replicationA systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cellsThe RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation.Regulation of p27 degradation and S-phase progression by Ro52 RING finger proteinBone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6C10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancerAntitumour effect of cyclin-dependent kinase inhibitors (p16(INK4A), p18(INK4C), p19(INK4D), p21(WAF1/CIP1) and p27(KIP1)) on malignant glioma cellsInterferon Regulatory Factor 1 (IRF-1) induces p21(WAF1/CIP1) dependent cell cycle arrest and p21(WAF1/CIP1) independent modulation of survivin in cancer cellsA growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damageInhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signalingCDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanismsDepletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growthCompetition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate.A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1RIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteinsLats2, a putative tumor suppressor, inhibits G1/S transitionC-terminal phosphorylation controls the stability and function of p27kip1The cyclin-dependent kinase inhibitors p15INK4B and p21CIP1 are critical regulators of fibrillar collagen-induced tumor cell cycle arrestPhosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phaseEffects of growth differentiation factor 9 on cell cycle regulators and ERK42/44 in human granulosa cell proliferationThe chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4aEvidence that low doses of Taxol enhance the functional transactivatory properties of p53 on p21 waf promoter in MCF-7 breast cancer cellsResponse gene to complement 32 is required for C5b-9 induced cell cycle activation in endothelial cellsCDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)Knockdown of protein tyrosine phosphatase SHP-1 inhibits G1/S progression in prostate cancer cells through the regulation of components of the cell-cycle machineryhSSB1 binds and protects p21 from ubiquitin-mediated degradation and positively correlates with p21 in human hepatocellular carcinomas
P2860
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P2860
CDK inhibitors: positive and negative regulators of G1-phase progression
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
CDK inhibitors: positive and negative regulators of G1-phase progression
@ast
CDK inhibitors: positive and negative regulators of G1-phase progression
@en
CDK inhibitors: positive and negative regulators of G1-phase progression
@nl
type
label
CDK inhibitors: positive and negative regulators of G1-phase progression
@ast
CDK inhibitors: positive and negative regulators of G1-phase progression
@en
CDK inhibitors: positive and negative regulators of G1-phase progression
@nl
prefLabel
CDK inhibitors: positive and negative regulators of G1-phase progression
@ast
CDK inhibitors: positive and negative regulators of G1-phase progression
@en
CDK inhibitors: positive and negative regulators of G1-phase progression
@nl
P3181
P356
P1433
P1476
CDK inhibitors: positive and negative regulators of G1-phase progression
@en
P2093
J M Roberts
P304
P3181
P356
10.1101/GAD.13.12.1501
P577
1999-06-15T00:00:00Z