Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11.
about
The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein familiesMuscarinic m1 receptor-stimulated adenylate cyclase activity in Chinese hamster ovary cells is mediated by Gs alpha and is not a consequence of phosphoinositidase C activationRegulation of a G protein-gated inwardly rectifying K+ channel by a Ca(2+)-independent protein kinase CG(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtypeRGS2 blocks slow muscarinic inhibition of N-type Ca(2+) channels reconstituted in a human cell lineDrosophila larval to pupal switch under nutrient stress requires IP3R/Ca(2+) signalling in glutamatergic interneuronsIdentification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.The muscarinic M(5) receptor: a silent or emerging subtype?Elementary events underlying voltage-dependent G-protein inhibition of N-type calcium channels.Differential effects of the Gβ5-RGS7 complex on muscarinic M3 receptor-induced Ca2+ influx and release.Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channelsComparison of the kinetics and extent of muscarinic M1-M5 receptor internalization, recycling and downregulation in Chinese hamster ovary cellsDual requirement for rho and protein kinase C in direct activation of phospholipase D1 through G protein-coupled receptor signalingEvidence for cross-talk between M2 and M3 muscarinic acetylcholine receptors in the regulation of second messenger and extracellular signal-regulated kinase signalling pathways in Chinese hamster ovary cellsAntagonism between G(o)alpha and G(q)alpha in Caenorhabditis elegans: the RGS protein EAT-16 is necessary for G(o)alpha signaling and regulates G(q)alpha activityMutations in a C. elegans Gqalpha gene disrupt movement, egg laying, and viability.M2 muscarinic receptors induce airway smooth muscle activation via a dual, Gbetagamma-mediated inhibition of large conductance Ca2+-activated K+ channel activity.A New Generation of FRET Sensors for Robust Measurement of Gαi1, Gαi2 and Gαi3 Activation Kinetics in Single CellsFulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.Regulators of G protein signaling attenuate the G protein-mediated inhibition of N-type Ca channelsPhospholipase D signaling: orchestration by PIP2 and small GTPases.Layer 2/3 synapses in monocular and binocular regions of tree shrew visual cortex express mAChR-dependent long-term depression and long-term potentiation.The origins of diversity and specificity in g protein-coupled receptor signalingTetrodotoxin-sensitive Na+ channels and muscarinic and purinergic receptors identified in human erythroid progenitor cells and red blood cell ghosts.Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery.A heterotrimeric G protein complex couples the muscarinic m1 receptor to phospholipase C-beta.Orthosteric- and allosteric-induced ligand-directed trafficking at GPCRs.New concepts in pharmacological efficacy at 7TM receptors: IUPHAR review 2.Biased agonism: An emerging paradigm in GPCR drug discovery.Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling.Muscarinic receptor subtypes and signalling involved in the attenuation of isoprenaline-induced rat urinary bladder relaxationQuantification of signalling components and amplification in the beta-adrenergic-receptor-adenylate cyclase pathway in isolated adult rat ventricular myocytes.Muscarinic Acetylcholine Receptor M3 activates GqA novel luminescence-based method for the detection of functionally active antibodies to muscarinic acetylcholine receptors of the M3 type (mAchR3) in patients' sera.
P2860
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P2860
Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11.
description
1994 nî lūn-bûn
@nan
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Transfected muscarinic acetylc ...... Gi-type G proteins and Gq/11.
@ast
Transfected muscarinic acetylc ...... Gi-type G proteins and Gq/11.
@en
Transfected muscarinic acetylc ...... Gi-type G proteins and Gq/11.
@nl
type
label
Transfected muscarinic acetylc ...... Gi-type G proteins and Gq/11.
@ast
Transfected muscarinic acetylc ...... Gi-type G proteins and Gq/11.
@en
Transfected muscarinic acetylc ...... Gi-type G proteins and Gq/11.
@nl
altLabel
Transfected muscarinic acetylc ...... o Gi-type G proteins and Gq/11
@en
prefLabel
Transfected muscarinic acetylc ...... Gi-type G proteins and Gq/11.
@ast
Transfected muscarinic acetylc ...... Gi-type G proteins and Gq/11.
@en
Transfected muscarinic acetylc ...... Gi-type G proteins and Gq/11.
@nl
P2093
P3181
P1476
Transfected muscarinic acetylc ...... Gi-type G proteins and Gq/11.
@en
P2093
J Sandmann
K H Jakobs
S Offermanns
P3181
P407
P577
1994-05-01T00:00:00Z