The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
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Robust network topologies for generating switch-like cellular responsesDeubiquitinases sharpen substrate discrimination during membrane protein degradation from the ERScaffold proteins: hubs for controlling the flow of cellular informationUltrasensitivity in multisite phosphorylation of membrane-anchored proteinsPhysicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Different levels of catabolite repression optimize growth in stable and variable environmentsComposite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligaseExploitation of latent allostery enables the evolution of new modes of MAP kinase regulationYeast adaptor protein, Nbp2p, is conserved regulator of fungal Ptc1p phosphatases and is involved in multiple signaling pathwaysRegulatory roles of phosphorylation in model and pathogenic fungiAn infrared reporter to detect spatiotemporal dynamics of protein-protein interactionsSignalling scaffolds and local organization of cellular behaviourScaffolds are 'active' regulators of signaling modulesEnzyme Sequestration as a Tuning Point in Controlling Response Dynamics of Signalling NetworksHow MAP kinase modules function as robust, yet adaptable, circuitsLight-activated kinases enable temporal dissection of signaling networks in living cells.Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.Spatial focalization of pheromone/MAPK signaling triggers commitment to cell-cell fusion.A fundamental trade-off in covalent switching and its circumvention by enzyme bifunctionality in glucose homeostasisA scalable double-barcode sequencing platform for characterization of dynamic protein-protein interactions.Cellular senescence and protein degradation: breaking down cancerThe calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identityReversible and noisy progression towards a commitment point enables adaptable and reliable cellular decision-making.Noise filtering tradeoffs in spatial gradient sensing and cell polarization response.Bell-shaped and ultrasensitive dose-response in phosphorylation-dephosphorylation cycles: the role of kinase-phosphatase complex formation.Diversity in genetic in vivo methods for protein-protein interaction studies: from the yeast two-hybrid system to the mammalian split-luciferase system.Commitment to lysogeny is preceded by a prolonged period of sensitivity to the late lytic regulator Q in bacteriophage λ.Utilization of the mating scaffold protein in the evolution of a new signal transduction pathway for biofilm development.Measuring fast gene dynamics in single cells with time-lapse luminescence microscopy.Assigning quantitative function to post-translational modifications reveals multiple sites of phosphorylation that tune yeast pheromone signaling outputDynamic modeling of yeast meiotic initiation.Ultrasensitivity in phosphorylation-dephosphorylation cycles with little substratePhosphoproteomic analyses reveal novel cross-modulation mechanisms between two signaling pathways in yeastAdaptation dynamics in densely clustered chemoreceptors.Determinants of cell-to-cell variability in protein kinase signaling.Scaffold-mediated nucleation of protein signaling complexes: elementary principles.Guidelines for visualizing and annotating rule-based modelsIn-vivo detection of binary PKA network interactions upon activation of endogenous GPCRsMAPK feedback encodes a switch and timer for tunable stress adaptation in yeast.A Predictive Model for Yeast Cell Polarization in Pheromone Gradients.
P2860
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P2860
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
@ast
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
@en
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
@nl
type
label
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
@ast
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
@en
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
@nl
altLabel
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast
@en
prefLabel
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
@ast
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
@en
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
@nl
P2093
P3181
P356
P1433
P1476
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast.
@en
P2093
Mohan K Malleshaiah
Stephen W Michnick
Vahid Shahrezaei
P2888
P3181
P356
10.1038/NATURE08946
P407
P577
2010-05-06T00:00:00Z
P5875
P6179
1010824234