Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry
about
A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicingSm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complexPartial purification of the yeast U2 snRNP reveals a novel yeast pre-mRNA splicing factor required for pre-spliceosome assemblyProteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.Characterization of U6 snRNA-protein interactions.Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiaeProteomic analysis of interchromatin granule clustersAnalysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptorsLarge-scale proteomic analysis of the human spliceosomeProtein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase IIInventories to insightsThe U1 snRNP-associated factor Luc7p affects 5' splice site selection in yeast and humanFunctional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs.Yeast pre-mRNA splicing requires a pair of U1 snRNP-associated tetratricopeptide repeat proteins.The identification of protein-protein interactions of the nuclear pore complex of Saccharomyces cerevisiae using high throughput matrix-assisted laser desorption ionization time-of-flight tandem mass spectrometry.New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing.A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins.The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2pInteraction of the U1 snRNP with nonconserved intronic sequences affects 5' splice site selection.Arrested yeast splicing complexes indicate stepwise snRNP recruitment during in vivo spliceosome assemblyLuc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition.Rds3p is required for stable U2 snRNP recruitment to the splicing apparatus.Rapid screening of yeast mutants with reporters identifies new splicing phenotypes.The yeast splicing factor Prp40p contains functional leucine-rich nuclear export signals that are essential for splicingPurification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors.A novel yeast U2 snRNP protein, Snu17p, is required for the first catalytic step of splicing and for progression of spliceosome assembly.Cbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA-binding protein, are present together with Gar1p in all H BOX/ACA-motif snoRNPs and constitute a common bipartite structure.Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particleMass spectrometry-based proteomicsYeast U1 snRNP-pre-mRNA complex formation without U1snRNA-pre-mRNA base pairing.Direct analysis of protein complexes using mass spectrometryThe use of bioreactive probes in protein characterization.Molecular biologist's guide to proteomicsA novel pathway that coordinates mitotic exit with spindle position.Interactions within the yeast Sm core complex: from proteins to amino acids.Proteome analysis of a human heptocellular carcinoma cell line, HCC-M: an update.Functional genomics by mass spectrometry.Uncovering the rules for protein-protein interactions from yeast genomic data.
P2860
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P248
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P2860
Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Identification of the proteins ...... n complex by mass spectrometry
@ast
Identification of the proteins ...... n complex by mass spectrometry
@en
Identification of the proteins ...... complex by mass spectrometry.
@nl
type
label
Identification of the proteins ...... n complex by mass spectrometry
@ast
Identification of the proteins ...... n complex by mass spectrometry
@en
Identification of the proteins ...... complex by mass spectrometry.
@nl
altLabel
Identification of the proteins ...... n complex by mass spectrometry
@en
prefLabel
Identification of the proteins ...... n complex by mass spectrometry
@ast
Identification of the proteins ...... n complex by mass spectrometry
@en
Identification of the proteins ...... complex by mass spectrometry.
@nl
P2093
P2860
P356
P1476
Identification of the proteins ...... n complex by mass spectrometry
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.2.385
P407
P577
1997-01-21T00:00:00Z