A spliceosomal recycling factor that reanneals U4 and U6 small nuclear ribonucleoprotein particles
about
A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicingGemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gemsProtein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing.Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodiesp110, a novel human U6 snRNP protein and U4/U6 snRNP recycling factorRNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodiesThe human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation.Human U4/U6 snRNP recycling factor p110: mutational analysis reveals the function of the tetratricopeptide repeat domain in recyclingIdentification of a PRPF4 loss-of-function variant that abrogates U4/U6.U5 tri-snRNP integration and is associated with retinitis pigmentosaRecycling of the U12-type spliceosome requires p110, a component of the U6atac snRNPThe U4/U6 recycling factor SART3 has histone chaperone activity and associates with USP15 to regulate H2B deubiquitinationCUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motifThe N- and C-terminal RNA recognition motifs of splicing factor Prp24 have distinct functions in U6 RNA bindingCharacterization of U6 snRNA-protein interactions.The 5' and 3' domains of yeast U6 snRNA: Lsm proteins facilitate binding of Prp24 protein to the U6 telestem regionA conserved Lsm-interaction motif in Prp24 required for efficient U4/U6 di-snRNP formationMultiple functions of Saccharomyces cerevisiae splicing protein Prp24 in U6 RNA structural rearrangementsDetection of snRNP assembly intermediates in Cajal bodies by fluorescence resonance energy transferStructure and interactions of the first three RNA recognition motifs of splicing factor prp24Structure and functional implications of a complex containing a segment of U6 RNA bound by a domain of Prp24A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loopMechanism for Aar2p function as a U5 snRNP assembly factorStructural basis for dual roles of Aar2p in U5 snRNP assemblyCore structure of the U6 small nuclear ribonucleoprotein at 1.7-Å resolutionElevated levels of a U4/U6.U5 snRNP-associated protein, Spp381p, rescue a mutant defective in spliceosome maturation.Yeast ntr1/spp382 mediates prp43 function in postspliceosomes.Prp43 is an essential RNA-dependent ATPase required for release of lariat-intron from the spliceosome.Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activationThe yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2pThe identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae.Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2.MRN1 implicates chromatin remodeling complexes and architectural factors in mRNA maturation.Genome-wide protein interaction screens reveal functional networks involving Sm-like proteinsPurification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.The ATP requirement for U2 snRNP addition is linked to the pre-mRNA region 5' to the branch site.In vivo kinetics of U4/U6·U5 tri-snRNP formation in Cajal bodies.A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing.A role for the yeast La protein in U6 snRNP assembly: evidence that the La protein is a molecular chaperone for RNA polymerase III transcriptsSplicing factor slt11p and its involvement in formation of U2/U6 helix II in activation of the yeast spliceosomeAll small nuclear RNAs (snRNAs) of the [U4/U6.U5] Tri-snRNP localize to nucleoli; Identification of the nucleolar localization element of U6 snRNA.
P2860
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P2860
A spliceosomal recycling factor that reanneals U4 and U6 small nuclear ribonucleoprotein particles
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A spliceosomal recycling facto ...... ar ribonucleoprotein particles
@ast
A spliceosomal recycling facto ...... ar ribonucleoprotein particles
@en
A spliceosomal recycling facto ...... ar ribonucleoprotein particles
@nl
type
label
A spliceosomal recycling facto ...... ar ribonucleoprotein particles
@ast
A spliceosomal recycling facto ...... ar ribonucleoprotein particles
@en
A spliceosomal recycling facto ...... ar ribonucleoprotein particles
@nl
prefLabel
A spliceosomal recycling facto ...... ar ribonucleoprotein particles
@ast
A spliceosomal recycling facto ...... ar ribonucleoprotein particles
@en
A spliceosomal recycling facto ...... ar ribonucleoprotein particles
@nl
P921
P3181
P1433
P1476
A spliceosomal recycling facto ...... r ribonucleoprotein particles.
@en
P2093
P L Raghunathan
P304
P3181
P356
10.1126/SCIENCE.279.5352.857
P407
P577
1998-02-06T00:00:00Z