Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein
about
Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexesMolecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.Mapping of residues forming the voltage sensor of the voltage-dependent anion-selective channelStructure and Activity of the Peptidyl-Prolyl Isomerase Domain from the Histone Chaperone Fpr4 toward Histone H3 Proline IsomerizationThe FKB2 gene of Saccharomyces cerevisiae, encoding the immunosuppressant-binding protein FKBP-13, is regulated in response to accumulation of unfolded proteins in the endoplasmic reticulumFKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity.Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.FKBP12 controls aspartate pathway flux in Saccharomyces cerevisiae to prevent toxic intermediate accumulation.Hmo1p, a high mobility group 1/2 homolog, genetically and physically interacts with the yeast FKBP12 prolyl isomeraseThe yeast immunophilin Fpr3 is a physiological substrate of the tyrosine-specific phosphoprotein phosphatase Ptp1.Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2.The nucleotide sequence of a third cyclophilin-homologous gene from Saccharomyces cerevisiae.All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae.A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus.Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug actionIdentification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residueBDNF activates mTOR to regulate GluR1 expression required for memory formationTomato FK506 Binding Protein 12KD (FKBP12) Mediates the Interaction between Rapamycin and Target of Rapamycin (TOR)TOR signaling.Cell growth control: little eukaryotes make big contributions.An integrated platform of genomic assays reveals small-molecule bioactivities.Calcineurin. Structure, function, and inhibition.Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans.ScFKBP12 bridges rapamycin and AtTOR in ArabidopsisIdentification and validation of protein targets of bioactive small moleculesThe TOR kinases link nutrient sensing to cell growth.Effects of rapamycin on cultured hepatocyte proliferation and gene expression.Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancerImmunophilins: structure-function relationship and possible role in microbial pathogenicity.The rapamycin-sensitive signal transduction pathway as a target for cancer therapy.Tailoring mTOR-based therapy: molecular evidence and clinical challenges.Peptidylproline cis-trans-isomerases: immunophilins.Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicityExploiting novel molecular targets in gastrointestinal cancers.Rapamycin increases rDNA stability by enhancing association of Sir2 with rDNA in Saccharomyces cerevisiaeSystematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth.Review series: TOR kinase complexes and cell migration.Target of rapamycin (TOR) in nutrient signaling and growth controlDeconvoluting mTOR biology
P2860
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P2860
Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein
description
1991 nî lūn-bûn
@nan
1991 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի մարտին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Rapamycin sensitivity in Sacch ...... to human FK506-binding protein
@ast
Rapamycin sensitivity in Sacch ...... to human FK506-binding protein
@en
Rapamycin sensitivity in Sacch ...... o human FK506-binding protein.
@nl
type
label
Rapamycin sensitivity in Sacch ...... to human FK506-binding protein
@ast
Rapamycin sensitivity in Sacch ...... to human FK506-binding protein
@en
Rapamycin sensitivity in Sacch ...... o human FK506-binding protein.
@nl
prefLabel
Rapamycin sensitivity in Sacch ...... to human FK506-binding protein
@ast
Rapamycin sensitivity in Sacch ...... to human FK506-binding protein
@en
Rapamycin sensitivity in Sacch ...... o human FK506-binding protein.
@nl
P2093
P2860
P356
P1476
Rapamycin sensitivity in Sacch ...... to human FK506-binding protein
@en
P2093
D J Bergsma
L Faucette
R Cafferkey
R K Johnson
P2860
P304
P356
10.1128/MCB.11.3.1718
P407
P577
1991-03-01T00:00:00Z