A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination.
about
TREX is a conserved complex coupling transcription with messenger RNA exportATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complexAly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNARecruitment of the human TREX complex to mRNA during splicingNuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP)A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae.The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability.Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1pMolecular evidence for a positive role of Spt4 in transcription elongation.Differential export requirements for shuttling serine/arginine-type mRNA-binding proteins.Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism.A new connection of mRNP biogenesis and export with transcription-coupled repairTho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutantsR-loop mediated transcription-associated recombination in trf4Δ mutants reveals new links between RNA surveillance and genome integrity.The Transcription Factor THO Promotes Transcription Initiation and Elongation by RNA Polymerase I.Zinc-regulated genes in Saccharomyces cerevisiae revealed by transposon tagging.A new hyperrecombination mutation identifies a novel yeast gene, THP1, connecting transcription elongation with mitotic recombination.Yeast spt6-140 mutation, affecting chromatin and transcription, preferentially increases recombination in which Rad51p-mediated strand exchange is dispensableNew suppressors of THO mutations identify Thp3 (Ypr045c)-Csn12 as a protein complex involved in transcription elongation.The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability.The role of TREX in gene expression and diseaseRNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeGenetic instability in budding and fission yeast-sources and mechanismsAn ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogrammingMethylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase IITransitions in RNA polymerase II elongation complexes at the 3' ends of genesTHOC5 controls 3'end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100).Spt4 modulates Rad26 requirement in transcription-coupled nucleotide excision repairFrequent gain and loss of functional transcription factor binding sites.Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiaeMechanism and regulation of transcriptional elongation by RNA polymerase II.A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expressionMitotic recombination in yeast: elements controlling its incidence.Stimulation of mitotic recombination events by high levels of RNA polymerase II transcription in yeastTFIIS enhances transcriptional elongation through an artificial arrest site in vivo.Imbalance of heterologous protein folding and disulfide bond formation rates yields runaway oxidative stress.RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instabilityCoupling of termination, 3' processing, and mRNA exportTranscriptional regulation of hTREX84 in human cancer cells.
P2860
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P2860
A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination.
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A novel yeast gene, THO2, is i ...... tion-associated recombination.
@ast
A novel yeast gene, THO2, is i ...... tion-associated recombination.
@en
A novel yeast gene, THO2, is i ...... tion-associated recombination.
@nl
type
label
A novel yeast gene, THO2, is i ...... tion-associated recombination.
@ast
A novel yeast gene, THO2, is i ...... tion-associated recombination.
@en
A novel yeast gene, THO2, is i ...... tion-associated recombination.
@nl
prefLabel
A novel yeast gene, THO2, is i ...... tion-associated recombination.
@ast
A novel yeast gene, THO2, is i ...... tion-associated recombination.
@en
A novel yeast gene, THO2, is i ...... tion-associated recombination.
@nl
P2860
P3181
P356
P1433
P1476
A novel yeast gene, THO2, is i ...... ation-associated recombination
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/17.16.4859
P407
P577
1998-08-01T00:00:00Z