Hsp70 nucleotide exchange factor Fes1 is essential for ubiquitin-dependent degradation of misfolded cytosolic proteins.
about
The nucleotide exchange factors of Hsp70 molecular chaperonesPhenotypes on demand via switchable target protein degradation in multicellular organisms.Prefoldin Promotes Proteasomal Degradation of Cytosolic Proteins with Missense Mutations by Maintaining Substrate Solubility.Hierarchical functional specificity of cytosolic heat shock protein 70 (Hsp70) nucleotide exchange factors in yeast.Coordinated Hsp110 and Hsp104 Activities Power Protein Disaggregation in Saccharomyces cerevisiae.Hsp70 clears misfolded kinases that partitioned into distinct quality-control compartments.Cytosolic splice isoform of Hsp70 nucleotide exchange factor Fes1 is required for the degradation of misfolded proteins in yeastChaperoning proteins for destruction: diverse roles of Hsp70 chaperones and their co-chaperones in targeting misfolded proteins to the proteasomeOpposing roles of Ubp3-dependent deubiquitination regulate replicative life span and heat resistance.Proteomic analysis of endoplasmic reticulum stress responses in rice seeds.Luciferase NanoLuc as a reporter for gene expression and protein levels in Saccharomyces cerevisiaeSubstrate binding by the yeast Hsp110 nucleotide exchange factor and molecular chaperone Sse1 is not obligate for its biological activities.Hsp70 cochaperones HspBP1 and BAG-1M differentially regulate steroid hormone receptor function.Polyamines directly promote antizyme-mediated degradation of ornithine decarboxylase by the proteasome.Identification of novel factors enhancing recombinant protein production in multi-copy Komagataella phaffii based on transcriptomic analysis of overexpression effects.Hsp70-associated chaperones have a critical role in buffering protein production costs.The absence of specific yeast heat-shock proteins leads to abnormal aggregation and compromised autophagic clearance of mutant Huntingtin proteins.Nucleotide exchange factors Fes1 and HspBP1 mimic substrate to release misfolded proteins from Hsp70.
P2860
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P2860
Hsp70 nucleotide exchange factor Fes1 is essential for ubiquitin-dependent degradation of misfolded cytosolic proteins.
description
2013 nî lūn-bûn
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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Hsp70 nucleotide exchange fact ...... misfolded cytosolic proteins.
@ast
Hsp70 nucleotide exchange fact ...... misfolded cytosolic proteins.
@en
Hsp70 nucleotide exchange fact ...... misfolded cytosolic proteins.
@nl
type
label
Hsp70 nucleotide exchange fact ...... misfolded cytosolic proteins.
@ast
Hsp70 nucleotide exchange fact ...... misfolded cytosolic proteins.
@en
Hsp70 nucleotide exchange fact ...... misfolded cytosolic proteins.
@nl
prefLabel
Hsp70 nucleotide exchange fact ...... misfolded cytosolic proteins.
@ast
Hsp70 nucleotide exchange fact ...... misfolded cytosolic proteins.
@en
Hsp70 nucleotide exchange fact ...... misfolded cytosolic proteins.
@nl
P2860
P50
P3181
P356
P1476
Hsp70 nucleotide exchange fact ...... f misfolded cytosolic proteins
@en
P2093
Ganapathi Kandasamy
Marceli S Froehlich
P2860
P304
P3181
P356
10.1073/PNAS.1216778110
P407
P577
2013-03-25T00:00:00Z