Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis.
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PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridgeStructural requirements for the recruitment of Gaa1 into a functional glycosylphosphatidylinositol transamidase complexPER1 is required for GPI-phospholipase A2 activity and involved in lipid remodeling of GPI-anchored proteinsThe initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component.Specificity of GlcNAc-PI de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors.Paroxysmal nocturnal hemoglobinuria from bench to bedsideThe glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA)Crystal structure of the conserved protein TT1542 fromThermus thermophilusHB8Crystal structure and functional characterization of a glucosamine-6-phosphate N-acetyltransferase from Arabidopsis thalianaGpi19, the Saccharomyces cerevisiae homologue of mammalian PIG-P, is a subunit of the initial enzyme for glycosylphosphatidylinositol anchor biosynthesis.GWT1 gene is required for inositol acylation of glycosylphosphatidylinositol anchors in yeast.Mammalian PIG-X and yeast Pbn1p are the essential components of glycosylphosphatidylinositol-mannosyltransferase I.Saccharomyces cerevisiae CWH43 is involved in the remodeling of the lipid moiety of GPI anchors to ceramidesYeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.GUP1 of Saccharomyces cerevisiae encodes an O-acyltransferase involved in remodeling of the GPI anchor.Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p.Pga1 is an essential component of Glycosylphosphatidylinositol-mannosyltransferase II of Saccharomyces cerevisiae.Analysis of membrane topology and identification of essential residues for the yeast endoplasmic reticulum inositol acyltransferase Gwt1p.The GPI transamidase complex of Saccharomyces cerevisiae contains Gaa1p, Gpi8p, and Gpi16p.PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor.GPI7 involved in glycosylphosphatidylinositol biosynthesis is essential for yeast cell separation.Ethanolaminephosphate side chain added to glycosylphosphatidylinositol (GPI) anchor by mcd4p is required for ceramide remodeling and forward transport of GPI proteins from endoplasmic reticulum to Golgi.Genes for glycosylphosphatidylinositol toxin biosynthesis in Plasmodium falciparum.PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesisPurification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei.Defects in myelination, paranode organization and Purkinje cell innervation in the ether lipid-deficient mouse cerebellumPGAP2 is essential for correct processing and stable expression of GPI-anchored proteinsStructural elucidation of novel phosphocholine-containing glycosylinositol-phosphoceramides in filamentous fungi and their induction of cell death of cultured rice cellsChemical validation of GPI biosynthesis as a drug target against African sleeping sickness.Bioinformatics and functional analysis of an Entamoeba histolytica mannosyltransferase necessary for parasite complement resistance and hepatical infection.Unique motifs identify PIG-A proteins from glycosyltransferases of the GT4 familyA hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC modelThe transposon impala is activated by low temperatures: use of a controlled transposition system to identify genes critical for viability of Aspergillus fumigatusComparative genomic and transcriptomic analysis of wangiella dermatitidis, a major cause of phaeohyphomycosis and a model black yeast human pathogenIntracellular glycosylphosphatidylinositols accumulate on endosomes: toxicity of alpha-toxin to Leishmania major.Synthetic Studies of Glycosylphosphatidylinositol (GPI) Anchors and GPI-Anchored Peptides, Glycopeptides, and ProteinsTransamidase subunit GAA1/GPAA1 is a M28 family metallo-peptide-synthetase that catalyzes the peptide bond formation between the substrate protein's omega-site and the GPI lipid anchor's phosphoethanolamine.The Awa1 gene is required for the foam-forming phenotype and cell surface hydrophobicity of sake yeast.Inositol deacylation by Bst1p is required for the quality control of glycosylphosphatidylinositol-anchored proteins.
P2860
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P2860
Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis.
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
Dissecting and manipulating th ...... linositol-anchor biosynthesis.
@ast
Dissecting and manipulating th ...... linositol-anchor biosynthesis.
@en
Dissecting and manipulating th ...... linositol-anchor biosynthesis.
@nl
type
label
Dissecting and manipulating th ...... linositol-anchor biosynthesis.
@ast
Dissecting and manipulating th ...... linositol-anchor biosynthesis.
@en
Dissecting and manipulating th ...... linositol-anchor biosynthesis.
@nl
prefLabel
Dissecting and manipulating th ...... linositol-anchor biosynthesis.
@ast
Dissecting and manipulating th ...... linositol-anchor biosynthesis.
@en
Dissecting and manipulating th ...... linositol-anchor biosynthesis.
@nl
P1476
Dissecting and manipulating th ...... linositol-anchor biosynthesis.
@en
P2093
P356
10.1016/S1367-5931(00)00151-4
P407
P577
2000-12-01T00:00:00Z