Dbf4-dependent CDC7 kinase links DNA replication to the segregation of homologous chromosomes in meiosis I.
about
The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachmentsThe Sum1/Ndt80 transcriptional switch and commitment to meiosis in Saccharomyces cerevisiaeFrom equator to pole: splitting chromosomes in mitosis and meiosisApplication of a new dual localization-affinity purification tag reveals novel aspects of protein kinase biology in Aspergillus nidulansSmc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisionsMonopolin subunit Csm1 associates with MIND complex to establish monopolar attachment of sister kinetochores at meiosis ITimeless links replication termination to mitotic kinase activationSaccharomyces cerevisiae Dbf4 Has Unique Fold Necessary for Interaction with Rad53 KinaseCrystal structure of human CDC7 kinase in complex with its activator DBF4PP2A(Cdc55)'s role in reductional chromosome segregation during achiasmate meiosis in budding yeast is independent of its FEAR function.Condensin suppresses recombination and regulates double-strand break processing at the repetitive ribosomal DNA array to ensure proper chromosome segregation during meiosis in budding yeast.Dbf4 regulates the Cdc5 Polo-like kinase through a distinct non-canonical binding interactionThe potent Cdc7-Dbf4 (DDK) kinase inhibitor XL413 has limited activity in many cancer cell lines and discovery of potential new DDK inhibitor scaffoldsCdc14 phosphatase directs centrosome re-duplication at the meiosis I to meiosis II transition in budding yeastMeikin is a conserved regulator of meiosis-I-specific kinetochore functionDDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approachCdc7-Dbf4 is a gene-specific regulator of meiotic transcription in yeastCDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor I with chromatin.The C-terminus of S. pombe DDK subunit Dfp1 is required for meiosis-specific transcription and cohesin cleavage.CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.A selfish DNA element engages a meiosis-specific motor and telomeres for germ-line propagation.A meiotic mystery: How sister kinetochores avoid being pulled in opposite directions during the first division.Tension-dependent removal of pericentromeric shugoshin is an indicator of sister chromosome biorientation.Fission yeast Hsk1 (Cdc7) kinase is required after replication initiation for induced mutagenesis and proper response to DNA alkylation damage.Meiotic recombination intermediates are resolved with minimal crossover formation during return-to-growth, an analogue of the mitotic cell cycleThe role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae.Cdc55 coordinates spindle assembly and chromosome disjunction during meiosis.Sister kinetochores are mechanically fused during meiosis I in yeast.A method for sporulating budding yeast cells that allows for unbiased identification of kinase substrates using stable isotope labeling by amino acids in cell culture.A genomic toolkit to investigate kinesin and myosin motor function in cells.Quantitative proteomics reveals a "poised quiescence" cellular state after triggering the DNA replication origin activation checkpoint.Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpointThe spindle checkpoint protein Mad2 regulates APC/C activity during prometaphase and metaphase of meiosis I in Saccharomyces cerevisiae.Meiosis: an overview of key differences from mitosis.Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae.Phosphorylation of Pkp1 by RIPK4 regulates epidermal differentiation and skin tumorigenesis.Cleavage of the SUN-domain protein Mps3 at its N-terminus regulates centrosome disjunction in budding yeast meiosis.Meiosis I chromosome segregation is established through regulation of microtubule-kinetochore interactions.A knockout screen for protein kinases required for the proper meiotic segregation of chromosomes in the fission yeast Schizosaccharomyces pombe.Phosphorylation: a key regulator of meiosis.
P2860
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P248
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P2860
Dbf4-dependent CDC7 kinase links DNA replication to the segregation of homologous chromosomes in meiosis I.
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Dbf4-dependent CDC7 kinase lin ...... gous chromosomes in meiosis I.
@ast
Dbf4-dependent CDC7 kinase lin ...... gous chromosomes in meiosis I.
@en
Dbf4-dependent CDC7 kinase lin ...... gous chromosomes in meiosis I.
@nl
type
label
Dbf4-dependent CDC7 kinase lin ...... gous chromosomes in meiosis I.
@ast
Dbf4-dependent CDC7 kinase lin ...... gous chromosomes in meiosis I.
@en
Dbf4-dependent CDC7 kinase lin ...... gous chromosomes in meiosis I.
@nl
prefLabel
Dbf4-dependent CDC7 kinase lin ...... gous chromosomes in meiosis I.
@ast
Dbf4-dependent CDC7 kinase lin ...... gous chromosomes in meiosis I.
@en
Dbf4-dependent CDC7 kinase lin ...... gous chromosomes in meiosis I.
@nl
P2093
P3181
P1433
P1476
Dbf4-dependent CDC7 kinase lin ...... gous chromosomes in meiosis I.
@en
P2093
Aliona Bogdanova
Andrej Shevchenko
Jesse J Lipp
Magno Junqueira
Sylvine Guillot
Wolfgang Zachariae
P304
P3181
P356
10.1016/J.CELL.2008.10.026
P407
P50
P577
2008-11-14T00:00:00Z