The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins.
about
A novel imprinted gene, encoding a RING zinc-finger protein, and overlapping antisense transcript in the Prader-Willi syndrome critical regionHuman pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factorsDistinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localizationThe poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNAInositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylationHuman Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase.Symplekin and multiple other polyadenylation factors participate in 3'-end maturation of histone mRNAsA CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF-100A new pathway in the control of the initiation of puberty: the MKRN3 genePoly(A) polymerase (PAP) diversity in gene expression--star-PAP vs canonical PAPStructure of Yeast Poly(A) Polymerase in Complex with a Peptide from Fip1, an Intrinsically Disordered Protein † ‡Structural basis for suppression of a host antiviral response by influenza A virusX-ray structures of NS1 effector domain mutantsThe 3'-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo.Mpe1, a zinc knuckle protein, is an essential component of yeast cleavage and polyadenylation factor required for the cleavage and polyadenylation of mRNA.Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast.Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor.Evidence that polyadenylation factor CPSF-73 is the mRNA 3' processing endonuclease.Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I.Fip1 regulates the activity of Poly(A) polymerase through multiple interactions.Distinct roles of two Yth1p domains in 3'-end cleavage and polyadenylation of yeast pre-mRNAs.Functional dissection of the zinc finger and flanking domains of the Yth1 cleavage/polyadenylation factor.Pti1p and Ref2p found in association with the mRNA 3' end formation complex direct snoRNA maturation.The end of the message: multiple protein-RNA interactions define the mRNA polyadenylation siteStructural biology of poly(A) site definitionFormation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesisNuclear-localized Asunder regulates cytoplasmic dynein localization via its role in the integrator complexThe CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target.Cysteine and histidine shuffling: mixing and matching cysteine and histidine residues in zinc finger proteins to afford different folds and function.Genome-wide survey and expression profiling of CCCH-zinc finger family reveals a functional module in macrophage activation.Distinctive interactions of the Arabidopsis homolog of the 30 kD subunit of the cleavage and polyadenylation specificity factor (AtCPSF30) with other polyadenylation factor subunitsDelineating the structural blueprint of the pre-mRNA 3'-end processing machinery.A large-scale insertional mutagenesis screen in zebrafishControl of cleavage site selection during mRNA 3' end formation by a yeast hnRNP.The cleavage and polyadenylation specificity factor in Xenopus laevis oocytes is a cytoplasmic factor involved in regulated polyadenylation.Arginine-rich regions mediate the RNA binding and regulatory activities of the protein encoded by the Drosophila melanogaster suppressor of sable gene.RBBP6 isoforms regulate the human polyadenylation machinery and modulate expression of mRNAs with AU-rich 3' UTRs.CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3' processingReconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33.Drosophila clipper/CPSF 30K is a post-transcriptionally regulated nuclear protein that binds RNA containing GC clusters.
P2860
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P2860
The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins.
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The 30-kD subunit of mammalian ...... -binding zinc finger proteins.
@ast
The 30-kD subunit of mammalian ...... -binding zinc finger proteins.
@en
The 30-kD subunit of mammalian ...... -binding zinc finger proteins.
@nl
type
label
The 30-kD subunit of mammalian ...... -binding zinc finger proteins.
@ast
The 30-kD subunit of mammalian ...... -binding zinc finger proteins.
@en
The 30-kD subunit of mammalian ...... -binding zinc finger proteins.
@nl
prefLabel
The 30-kD subunit of mammalian ...... -binding zinc finger proteins.
@ast
The 30-kD subunit of mammalian ...... -binding zinc finger proteins.
@en
The 30-kD subunit of mammalian ...... -binding zinc finger proteins.
@nl
P2093
P356
P1433
P1476
The 30-kD subunit of mammalian ...... -binding zinc finger proteins.
@en
P2093
L Minvielle-Sebastia
S M Barabino
P304
P356
10.1101/GAD.11.13.1703
P407
P577
1997-07-01T00:00:00Z