Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation.
about
Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotesOB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulationRegulating telomere length from the inside out: the replication fork modelTelomere- and Telomerase-Associated Proteins and Their Functions in the Plant CellStructure and function of the telomeric CST complexStn1-Ten1 is an Rpa2-Rpa3-like complex at telomeresStructural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase αAnalyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70Cdc13 OB2 Dimerization Required for Productive Stn1 Binding and Efficient Telomere MaintenanceStructural Basis for the Interaction of a Hexameric Replicative Helicase with the Regulatory Subunit of Human DNA Polymerase -PrimaseThe THO complex component Thp2 counteracts telomeric R-loops and telomere shorteningTen1p promotes the telomeric DNA-binding activity of Cdc13p: implication for its function in telomere length regulation.The role of Stn1p in Saccharomyces cerevisiae telomere capping can be separated from its interaction with Cdc13p.Chromosome end protection plasticity revealed by Stn1p and Ten1p bypass of Cdc13p.Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.RPA facilitates telomerase activity at chromosome ends in budding and fission yeastsThe telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with G-Tails, and unfolds higher-order G-tail structuresCTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustionAberrant DNA polymerase alpha is excluded from the nucleus by defective import and degradation in the nucleusAlterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase alpha.Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition.Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres.Fission yeast Stn1 is crucial for semi-conservative replication at telomeres and subtelomeres.Protection and replication of telomeres in fission yeast.Rif1 supports the function of the CST complex in yeast telomere capping.To fuse or not to fuse: how do checkpoint and DNA repair proteins maintain telomeres?A mutation in the STN1 gene triggers an alternative lengthening of telomere-like runaway recombinational telomere elongation and rapid deletion in yeast.Xenopus laevis Ctc1-Stn1-Ten1 (xCST) protein complex is involved in priming DNA synthesis on single-stranded DNA template in Xenopus egg extract.Evolution of CST function in telomere maintenance.Genome-wide screen reveals replication pathway for quasi-palindrome fragility dependent on homologous recombination.Role of STN1 and DNA polymerase α in telomere stability and genome-wide replication in Arabidopsis.Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit.A POT1 mutation implicates defective telomere end fill-in and telomere truncations in Coats plusTying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at Telomeres.Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.Chromosome end protection by blunt-ended telomeresReplication of telomeres and the regulation of telomerase.DNA repair at telomeres: keeping the ends intact.Yeast telomere capping protein Stn1 overrides DNA replication control through the S phase checkpointCST for the grand finale of telomere replication.
P2860
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P2860
Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation.
description
2004 nî lūn-bûn
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2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2004 թվականի մայիսին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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2004年论文
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Pol12, the B subunit of DNA po ...... capping and length regulation.
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Pol12, the B subunit of DNA po ...... capping and length regulation.
@en
Pol12, the B subunit of DNA po ...... capping and length regulation.
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Pol12, the B subunit of DNA po ...... capping and length regulation.
@ast
Pol12, the B subunit of DNA po ...... capping and length regulation.
@en
Pol12, the B subunit of DNA po ...... capping and length regulation.
@nl
prefLabel
Pol12, the B subunit of DNA po ...... capping and length regulation.
@ast
Pol12, the B subunit of DNA po ...... capping and length regulation.
@en
Pol12, the B subunit of DNA po ...... capping and length regulation.
@nl
P2093
P2860
P3181
P356
P1433
P1476
Pol12, the B subunit of DNA po ...... capping and length regulation.
@en
P2093
Andrea Puglisi
David Shore
Massimo Lopes
Petr V Dmitriev
Simona Grossi
P2860
P304
P3181
P356
10.1101/GAD.300004
P407
P577
2004-05-01T00:00:00Z