A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants
about
Yeast Nucleoporins Involved in Passive Nuclear Envelope PermeabilityNuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells.Functional architecture in the cell nucleusYtm1, Nop7, and Erb1 form a complex necessary for maturation of yeast 66S preribosomesNog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation stepsYeast Pescadillo is required for multiple activities during 60S ribosomal subunit synthesis.Functional link between ribosome formation and biogenesis of iron-sulfur proteinsSequential protein association with nascent 60S ribosomal particlesIn vivo labelling of functional ribosomes reveals spatial regulation during starvation in Podospora anserinaSac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex.A pre-ribosome-associated HEAT-repeat protein is required for export of both ribosomal subunits.Factors affecting nuclear export of the 60S ribosomal subunit in vivoBinding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export.A versatile interaction platform on the Mex67-Mtr2 receptor creates an overlap between mRNA and ribosome export.Rational extension of the ribosome biogenesis pathway using network-guided geneticsA ribosome-anchored chaperone network that facilitates eukaryotic ribosome biogenesisNuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins.Intersection of the Kap123p-mediated nuclear import and ribosome export pathwaysBiogenesis of the signal recognition particle (SRP) involves import of SRP proteins into the nucleolus, assembly with the SRP-RNA, and Xpo1p-mediated export.Rea1, a dynein-related nuclear AAA-ATPase, is involved in late rRNA processing and nuclear export of 60 S subunits.A nuclear AAA-type ATPase (Rix7p) is required for biogenesis and nuclear export of 60S ribosomal subunits.Assembly factors Rpf2 and Rrs1 recruit 5S rRNA and ribosomal proteins rpL5 and rpL11 into nascent ribosomesYeast ribosomal protein L40 assembles late into precursor 60 S ribosomes and is required for their cytoplasmic maturationYvh1 is required for a late maturation step in the 60S biogenesis pathway.A Noc complex specifically involved in the formation and nuclear export of ribosomal 40 S subunits.Mrd1p is required for processing of pre-rRNA and for maintenance of steady-state levels of 40 S ribosomal subunits in yeast.Ltv1 is required for efficient nuclear export of the ribosomal small subunit in Saccharomyces cerevisiaeYeast polypeptide exit tunnel ribosomal proteins L17, L35 and L37 are necessary to recruit late-assembling factors required for 27SB pre-rRNA processing.The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeastCoupled GTPase and remodelling ATPase activities form a checkpoint for ribosome export.The p21-activated protein kinase inhibitor Skb15 and its budding yeast homologue are 60S ribosome assembly factors.Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex.Nuclear accumulation of the small GTPase Gsp1p depends on nucleoporins Nup133p, Rat2p/Nup120p, Nup85p, Nic96p, and the acetyl-CoA carboxylase Acc1p.Nuclear export of 60s ribosomal subunits depends on Xpo1p and requires a nuclear export sequence-containing factor, Nmd3p, that associates with the large subunit protein Rpl10p.Trm112 is required for Bud23-mediated methylation of the 18S rRNA at position G1575.A functional network involved in the recycling of nucleocytoplasmic pre-60S factors.Nmd3p is a Crm1p-dependent adapter protein for nuclear export of the large ribosomal subunit.Novel interaction of the 60S ribosomal subunit export adapter Nmd3 at the nuclear pore complex.Distinct cytoplasmic maturation steps of 40S ribosomal subunit precursors require hRio2Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis
P2860
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P2860
A novel in vivo assay reveals inhibition of ribosomal nuclear export in ran-cycle and nucleoporin mutants
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A novel in vivo assay reveals ...... -cycle and nucleoporin mutants
@ast
A novel in vivo assay reveals ...... -cycle and nucleoporin mutants
@en
A novel in vivo assay reveals ...... cycle and nucleoporin mutants.
@nl
type
label
A novel in vivo assay reveals ...... -cycle and nucleoporin mutants
@ast
A novel in vivo assay reveals ...... -cycle and nucleoporin mutants
@en
A novel in vivo assay reveals ...... cycle and nucleoporin mutants.
@nl
prefLabel
A novel in vivo assay reveals ...... -cycle and nucleoporin mutants
@ast
A novel in vivo assay reveals ...... -cycle and nucleoporin mutants
@en
A novel in vivo assay reveals ...... cycle and nucleoporin mutants.
@nl
P2093
P2860
P3181
P356
P1476
A novel in vivo assay reveals ...... -cycle and nucleoporin mutants
@en
P2093
P2860
P304
P3181
P356
10.1083/JCB.144.3.389
P407
P577
1999-02-08T00:00:00Z