Biosynthesis of diphthamide in Saccharomyces cerevisiae. Partial purification and characterization of a specific S-adenosylmethionine:elongation factor 2 methyltransferase
about
Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2Increased phosphorylation of elongation factor 2 during mitosis in transformed human amnion cells correlates with a decreased rate of protein synthesisMechanism and regulation of eukaryotic protein synthesisDPH5, a methyltransferase gene required for diphthamide biosynthesis in Saccharomyces cerevisiae.Dph7 catalyzes a previously unknown demethylation step in diphthamide biosynthesis.The amidation step of diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction networkThe biosynthesis and biological function of diphthamideA dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin A and diphtheria toxinReconstitution of diphthine synthase activity in vitro.Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse developmentDidehydrophenylalanine, an abundant modification in the beta subunit of plant polygalacturonases.The diphthamide modification on elongation factor-2 renders mammalian cells resistant to ricin.Radical S-adenosylmethionine enzymes.Importance of diphthamide modified EF2 for translational accuracy and competitive cell growth in yeast
P2860
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P2860
Biosynthesis of diphthamide in Saccharomyces cerevisiae. Partial purification and characterization of a specific S-adenosylmethionine:elongation factor 2 methyltransferase
description
1988 nî lūn-bûn
@nan
1988 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Biosynthesis of diphthamide in ...... ion factor 2 methyltransferase
@ast
Biosynthesis of diphthamide in ...... ion factor 2 methyltransferase
@en
Biosynthesis of diphthamide in ...... ion factor 2 methyltransferase
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type
label
Biosynthesis of diphthamide in ...... ion factor 2 methyltransferase
@ast
Biosynthesis of diphthamide in ...... ion factor 2 methyltransferase
@en
Biosynthesis of diphthamide in ...... ion factor 2 methyltransferase
@nl
prefLabel
Biosynthesis of diphthamide in ...... ion factor 2 methyltransferase
@ast
Biosynthesis of diphthamide in ...... ion factor 2 methyltransferase
@en
Biosynthesis of diphthamide in ...... ion factor 2 methyltransferase
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P1476
Biosynthesis of diphthamide in ...... on factor 2 methyltransferase.
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P2093
P304
P407
P577
1988-08-25T00:00:00Z