Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
about
The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activityTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationBiochemical analysis of human Dna2Mapping of a major locus that determines telomere length in humansRolling-circle transposons in eukaryotesThe telomere syndromesTelomere dysfunction and chromosome instabilityThe yeast Pif1p helicase removes telomerase from telomeric DNA.Telomerase-null survivor screening identifies novel telomere recombination regulators.Yeast Pif1 helicase exhibits a one-base-pair stepping mechanism for unwinding duplex DNAPif1 family helicases suppress genome instability at G-quadruplex motifs.Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replicationDef1p is involved in telomere maintenance in budding yeast.Yeast Pif1 accelerates annealing of complementary DNA strands.Saccharomyces Rrm3p, a 5' to 3' DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA.Evidence for a role of FEN1 in maintaining mitochondrial DNA integrityAlternative translation initiation augments the human mitochondrial proteomePfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome IntegrityMurine Pif1 interacts with telomerase and is dispensable for telomere function in vivoSgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break endsCrystal structures of the BsPif1 helicase reveal that a major movement of the 2B SH3 domain is required for DNA unwindingDNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures.Sensitivity of yeast strains with long G-tails to levels of telomere-bound telomerase.The yeast Pif1p DNA helicase preferentially unwinds RNA DNA substratesMph1p promotes gross chromosomal rearrangement through partial inhibition of homologous recombination.Increased genome instability and telomere length in the elg1-deficient Saccharomyces cerevisiae mutant are regulated by S-phase checkpoints.Effect of telomere proximity on telomere position effect, chromosome healing, and sensitivity to DNA double-strand breaks in a human tumor cell line.Inactivation of Pif1 helicase causes a mitochondrial myopathy in miceUnwinding the functions of the Pif1 family helicases.A mutation in the catalytic subunit of yeast telomerase alters primer-template alignment while promoting processivity and protein-DNA binding.Pathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiaeMultiplexed gene control reveals rapid mRNA turnover.Schizosaccharomyces pombe pfh1+ encodes an essential 5' to 3' DNA helicase that is a member of the PIF1 subfamily of DNA helicases.Repair of chromosome ends after telomere loss in Saccharomyces.Pif1 regulates telomere length by preferentially removing telomerase from long telomere endsGenetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae.Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae.Mitochondrial helicases and mitochondrial genome maintenanceTelomeres: structures in need of unwinding.Telomere loss as a mechanism for chromosome instability in human cancer
P2860
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P2860
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
@ast
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
@en
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
@nl
type
label
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
@ast
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
@en
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
@nl
prefLabel
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
@ast
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
@en
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
@nl
P2093
P3181
P1433
P1476
Pif1p helicase, a catalytic inhibitor of telomerase in yeast.
@en
P2093
P3181
P356
10.1126/SCIENCE.289.5480.771
P407
P577
2000-08-04T00:00:00Z