about
The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexesESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozymePhosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase ICarbonic anhydrase inhibitors: the X-ray crystal structure of the adduct of N-hydroxysulfamide with isozyme II explains why this new zinc binding function is effective in the design of potent inhibitorsCarbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: kinetic and X-ray crystallographic studiesCarbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studiesCarbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studiesCarbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adductCarbonic anhydrase inhibitors. Interaction of the antitumor sulfamate EMD 486019 with twelve mammalian carbonic anhydrase isoforms: Kinetic and X-ray crystallographic studiesCarbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIVCarbonic anhydrase inhibitors. Comparison of chlorthalidone and indapamide X-ray crystal structures in adducts with isozyme II: when three water molecules and the keto-enol tautomerism make the differenceA thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrasesNon-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitorsDissecting the inhibition mechanism of cytosolic versus transmembrane carbonic anhydrases by ESRNitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucomaDeciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarinsCarbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II-trithiocarbonate adduct--an inhibitor mimicking the sulfonamide and urea binding to the enzymeThe coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitorsPolyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water moleculeThe x-ray structure of the adduct between NAMI-A and carbonic anhydrase provides insights into the reactivity of this metallodrug with proteinsSynthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Claudia Temperini
@ast
Claudia Temperini
@en
Claudia Temperini
@es
Claudia Temperini
@sl
type
label
Claudia Temperini
@ast
Claudia Temperini
@en
Claudia Temperini
@es
Claudia Temperini
@sl
prefLabel
Claudia Temperini
@ast
Claudia Temperini
@en
Claudia Temperini
@es
Claudia Temperini
@sl