Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer

Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer

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http://www.wikidata.org/entity/Q28073257
Downregulation of UHRF1 increases tumor malignancy by activating the CXCR4/AKT-JNK/IL-6/Snail signaling axis in hepatocellular carcinoma cells.Functional dissection of the role of UHRF1 in the regulation of retinoblastoma methylome.The epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer.Conformational dynamics of the TTD-PHD histone reader module of the UHRF1 epigenetic regulator reveals multiple histone-binding states, allosteric regulation, and druggability.Targeting microRNA/UHRF1 pathways as a novel strategy for cancer therapy.Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell.UHRF1 depletion sensitizes retinoblastoma cells to chemotherapeutic drugs via downregulation of XRCC4.Overexpression of UHRF1 promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma.Maintenance and pharmacologic targeting of ROR1 protein levels via UHRF1 in t(1;19) pre-B-ALL.Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger-containing 1 (UHRF1) for anti-cancer drug development.The Extract of Leonurus sibiricus Transgenic Roots with AtPAP1 Transcriptional Factor Induces Apoptosis via DNA Damage and Down Regulation of Selected Epigenetic Factors in Human Cancer Cells.Thymoquinone challenges UHRF1 to commit auto-ubiquitination: a key event for apoptosis induction in cancer cells.PARP inhibitor veliparib and HDAC inhibitor SAHA synergistically co-target the UHRF1/BRCA1 DNA damage repair complex in prostate cancer cells
P2860

Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer

Item
http://www.wikidata.org/entity/Q28073257
description
2016 nî lūn-bûn
@nan
2016 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
@ast
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
@en
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
@nl
type
label
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
@ast
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
@en
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
@nl
prefLabel
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
@ast
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
@en
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
@nl
P1433
P1476
P2093
P275
P2860
P2888
P304
P31
P3181
P356
P407
P433
P478
P50
P5008
P577
P6179
P698
P921
P932
P3181
P356
P1433
P1476
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancer
@en
P2093
P275
P2860
P2888
P304
P31
P3181
P356
P407
P433
P478
P50
P5008
P577
P6179
P698
P921
P932