Sodium channel β subunits: emerging targets in channelopathies - Wikidata - awgldk - TriplyDB

Sodium channel β subunits: emerging targets in channelopathies

Sodium channel β subunits: emerging targets in channelopathies

http://www.wikidata.org/entity/Q28082122

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Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery The hitchhiker's guide to the voltage-gated sodium channel galaxy Mechanisms of sodium channel clustering and its influence on axonal impulse conduction Voltage-gated sodium channels and cancer: is excitability their primary role?Ion channel macromolecular complexes in cardiomyocytes: roles in sudden cardiac death Protein mutated in paroxysmal dyskinesia interacts with the active zone protein RIM and suppresses synaptic vesicle exocytosis Axonal Membranes and Their Domains: Assembly and Function of the Axon Initial Segment and Node of Ranvier.More than a pore: ion channel signaling complexes β1-C121W Is Down But Not Out: Epilepsy-Associated Scn1b-C121W Results in a Deleterious Gain-of-Function.SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer Ankyrin G Membrane Partners Drive the Establishment and Maintenance of the Axon Initial Segment Trafficking and localisation to the plasma membrane of Nav 1.5 promoted by the β2 subunit is defective due to a β2 mutation associated with Brugada syndrome.Voltage-Gated Na+ Channels: Not Just for Conduction.Ion channel regulation by β-secretase BACE1 - enzymatic and non-enzymatic effects beyond Alzheimer's disease.Modulation of Ionic Channels and Insulin Secretion by Drugs and Hormones in Pancreatic Beta Cells.Murine Electrophysiological Models of Cardiac Arrhythmogenesis.Cellular encoding of Cy dyes for single-molecule imaging.The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional Implications and Regulatory Mechanisms.Interactive effects of maternal cigarette smoke, heat stress, hypoxia, and lipopolysaccharide on neonatal cardiorespiratory and cytokine responses.Mutation E87Q of the β1-subunit impairs the maturation of the cardiac voltage-dependent sodium channel.Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit.Sodium Channel β Subunits in Epilepsy: Location, Location, Location.µ-Conotoxins Modulating Sodium Currents in Pain Perception and Transmission: A Therapeutic Potential.Scn2b Deletion in Mice Results in Ventricular and Atrial Arrhythmias.NaV Channels: Assaying Biosynthesis, Trafficking, Function.Ion Channels in Genetic Epilepsy: From Genes and Mechanisms to Disease-Targeted Therapies.Voltage-Gated Sodium Channel β Subunits and Their Related Diseases.Mechanisms and models of cardiac sodium channel inactivation.Voltage-gated sodium channel β subunits: The power outside the pore in brain development and disease.Backbone resonance assignments of complexes of human voltage-dependent sodium channel NaV1.2 IQ motif peptide bound to apo calmodulin and to the C-domain fragment of apo calmodulin.Distribution and function of voltage-gated sodium channels in the nervous system.[Navβ4: a metastasis suppressor and a new biomarker of aggressive cancers].Cell Membrane Transport Mechanisms: Ion Channels and Electrical Properties of Cell Membranes.Preserved SCN4B expression is an independent indicator of favorable recurrence-free survival in classical papillary thyroid cancer.Voltage-Gated Sodium Channel β1/β1B Subunits Regulate Cardiac Physiology and Pathophysiology.Mutations in SCN3A cause early infantile epileptic encephalopathy The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation

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Sodium channel β subunits: emerging targets in channelopathies

http://www.wikidata.org/entity/Q28082122

description

2015 nî lūn-bûn

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2015 թուականին հրատարակուած գիտական յօդուած

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2015 թվականին հրատարակված գիտական հոդված

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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name

Sodium channel β subunits: emerging targets in channelopathies

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Sodium channel β subunits: emerging targets in channelopathies

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Sodium channel β subunits: emerging targets in channelopathies

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Sodium channel β subunits: emerging targets in channelopathies

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Sodium channel β subunits: emerging targets in channelopathies

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Sodium channel β subunits: emerging targets in channelopathies

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Sodium channel β subunits: emerging targets in channelopathies

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Sodium channel β subunits: emerging targets in channelopathies

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Sodium channel β subunits: emerging targets in channelopathies

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ANNUREV-PHYSIOL-021014-071846

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Annual Review of Physiology

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Sodium channel β subunits: emerging targets in channelopathies

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Heather A. O'Malley

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Lori L. Isom

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P2860

Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome

beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics

Loss-of-function mutation of the SCN3B-encoded sodium channel {beta}3 subunit associated with a case of idiopathic ventricular fibrillation

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals

Molecular cloning and functional expression of the human sodium channel beta1B subunit, a novel splicing variant of the beta1 subunit

Sudden infant death syndrome-associated mutations in the sodium channel beta subunits

Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation

Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans

Crystallographic insights into sodium-channel modulation by the β4 subunit

SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome

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481-504

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scholarly article

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1741195

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10.1146/ANNUREV-PHYSIOL-021014-071846

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77

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2015-01-01T00:00:00Z

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