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The organic anion transporter (OAT) family: a systems biology perspective

The organic anion transporter (OAT) family: a systems biology perspective

http://www.wikidata.org/entity/Q28085671

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The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids Probenecid and N-Acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs An Integrated View of Aristolochic Acid Nephropathy: Update of the Literature Acute effects of focused ultrasound-induced increases in blood-brain barrier permeability on rat microvascular transcriptome.Interactions of 172 plant extracts with human organic anion transporter 1 (SLC22A6) and 3 (SLC22A8): a study on herb-drug interactions.Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children.Drug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 Proteins Transcriptome-based reconstructions from the murine knockout suggest involvement of the urate transporter, URAT1 (slc22a12), in novel metabolic pathways Multispecific Organic Cation Transporter 1 (OCT1) from Bos taurus Has High Affinity and Slow Binding Kinetics towards Prostaglandin E2.Phylogenetic, syntenic, and tissue expression analysis of slc22 genes in zebrafish (Danio rerio).Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters.Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors What do drug transporters really do?Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling.Growth hormone treatment of premature ovarian failure in a mouse model via stimulation of the Notch-1 signaling pathway.Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers.The importance of drug transporters in human pluripotent stem cells and in early tissue differentiation.The drug transporter OAT3 (SLC22A8) regulates endogenous metabolite flow through the gut-liver-kidney axis.Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes Role of Organic Anion Transporters in the Uptake of Protein-Bound Uremic Toxins by Human Endothelial Cells and Monocyte Chemoattractant Protein-1 Expression.The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?The Choroid Plexus in Healthy and Diseased Brain.Uric acid transporters hiding in the intestine.Loops and layers of post-translational modifications of drug transporters.Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1.Transporter effects on cell permeability in drug delivery.Role of Passive Diffusion, Transporters, and Membrane Trafficking-Mediated Processes in Cellular Drug Transport.Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and research priorities.Trafficking and other regulatory mechanisms for organic anion transporting polypeptides and organic anion transporters that modulate cellular drug and xenobiotic influx and that are dysregulated in disease.Efflux proteins at the blood-brain barrier: review and bioinformatics analysis.Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer.Compensatory Renal Hypertrophy and the Uptake of Cysteine S-Conjugates of Hg2+ in Isolated S2 Proximal Tubular Segments.An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network.Uptake and metabolism of sulphated steroids by the blood-brain barrier in the adult male rat.Human rickettsial pathogen modulates arthropod organic anion transporting polypeptide and tryptophan pathway for its survival in ticks Recent advances on uric acid transporters.Reference values of renal tubular function tests are dependent on age and kidney function.Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk.From the Cover: Identification of Natural Products as Inhibitors of Human Organic Anion Transporters (OAT1 and OAT3) and Their Protective Effect on Mercury-Induced Toxicity.

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The organic anion transporter (OAT) family: a systems biology perspective

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2015年の論文

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2015年論文

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name

The organic anion transporter (OAT) family: a systems biology perspective

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The organic anion transporter (OAT) family: a systems biology perspective

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The organic anion transporter (OAT) family: a systems biology perspective

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The organic anion transporter (OAT) family: a systems biology perspective

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The organic anion transporter (OAT) family: a systems biology perspective

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The organic anion transporter (OAT) family: a systems biology perspective

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PHYSREV.00025.2013

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Physiological Reviews

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The organic anion transporter (OAT) family: a systems biology perspective

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Erin Richard

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Gleb Martovetsky

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Henry C Liu

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Kevin T Bush

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Sanjay K Nigam

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Vibha Bhatnagar

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Wei Wu

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P2860

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

Characterizing the expression of the human olfactory receptor gene family using a novel DNA microarray

Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3 and ORCTL4, bearing homology to organic-cation transporters

Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

An integrated encyclopedia of DNA elements in the human genome

Molecular identification of a renal urate anion exchanger that regulates blood urate levels

Liver X receptor activation downregulates organic anion transporter 1 (OAT1) in the renal proximal tubule

The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus

Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate

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10.1152/PHYSREV.00025.2013

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