Going beyond the liver: progress and challenges of targeted delivery of siRNA therapeutics
about
Intracellular targeting with engineered proteinsExploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish modelsTherapeutic Oligonucleotides Targeting Liver Disease: TTR AmyloidosisOligonucleotide Therapies: The Past and the PresentDesign, synthesis and evaluation of VEGF-siRNA/CRS as a novel vector for gene deliveryApproaches to Validate and Manipulate RNA Targets with Small Molecules in CellsTranslation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNAThe notorious R.N.A. in the spotlight - drug or target for the treatment of diseaseEvaluation of Therapeutic Oligonucleotides for Familial Amyloid Polyneuropathy in Patient-Derived Hepatocyte-Like Cells.Current development of targeted oligonucleotide-based cancer therapies: Perspective on HER2-positive breast cancer treatment.The delivery of therapeutic oligonucleotidesSilencing CCR2 in Macrophages Alleviates Adipose Tissue Inflammation and the Associated Metabolic Syndrome in Dietary Obese Mice.Lipid Nanoparticle-mediated siRNA Transfer Against PCTAIRE1/PCTK1/Cdk16 Inhibits In Vivo Cancer Growth.Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells.Systemic activation of antigen-presenting cells via RNA-loaded nanoparticles.CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors.Therapeutic oligonucleotides with polyethylene glycol modifications.Pharmacokinetics and biodistribution of recently-developed siRNA nanomedicinesImaging-guided delivery of RNAi for anticancer treatment.Effect of IL-1β, TNF-α and IGF-1 on trans-endothelial passage of synthetic vectors through an in vitro vascular endothelial barrier of striated muscle.Conjugation of curcumin-loaded lipid nanoemulsions with cell-penetrating peptides increases their cellular uptake and enhances the anti-inflammatory effects in endothelial cells.Concise postsynthetic preparation of oligonucleotide-oligopeptide conjugates through facile disulfide bond formation.Optimal Hydrophobicity in Ring-Opening Metathesis Polymerization-Based Protein Mimics Required for siRNA Internalization.Engineered Hydrogels for Local and Sustained Delivery of RNA-Interference Therapies.Silencing the roadblocks to effective triple-negative breast cancer treatments by siRNA nanoparticles.The Race of 10 Synthetic RNAi-Based Drugs to the Pharmaceutical Market.HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells.Variable asialoglycoprotein receptor 1 expression in liver disease: Implications for therapeutic intervention.Delivery of gene targeting siRNAs to breast cancer cells using a multifunctional peptide complex that promotes both targeted delivery and endosomal release.Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran.High-Contrast Fluorescence Detection of Metastatic Breast Cancer Including Bone and Liver Micrometastases via Size-Controlled pH-Activatable Water-Soluble Probes.RNAi-Mediated Knockdown of Protein Expression.Controlled and sustained delivery of siRNA/NPs from hydrogels expedites bone fracture healing.Translational Advances in the Field of Pulmonary Hypertension. Translating MicroRNA Biology in Pulmonary Hypertension. It Will Take More Than "miR" Words."Clicking" gene therapeutics: A successful union of chemistry and biomedicine for new solutions.Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives.Development of Controlled Drug Delivery Systems for Bone Fracture-Targeted Therapeutic Delivery: A Review.Development of bioactive materials for glioblastoma therapy.Cholecystokinin Receptor-Targeted Polyplex Nanoparticle Inhibits Growth and Metastasis of Pancreatic Cancer.Current Challenges in Delivery and Cytosolic Translocation of Therapeutic RNAs.
P2860
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P2860
Going beyond the liver: progress and challenges of targeted delivery of siRNA therapeutics
description
2015 nî lūn-bûn
@nan
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Going beyond the liver: progre ...... delivery of siRNA therapeutics
@ast
Going beyond the liver: progre ...... delivery of siRNA therapeutics
@en
Going beyond the liver: progre ...... delivery of siRNA therapeutics
@nl
type
label
Going beyond the liver: progre ...... delivery of siRNA therapeutics
@ast
Going beyond the liver: progre ...... delivery of siRNA therapeutics
@en
Going beyond the liver: progre ...... delivery of siRNA therapeutics
@nl
prefLabel
Going beyond the liver: progre ...... delivery of siRNA therapeutics
@ast
Going beyond the liver: progre ...... delivery of siRNA therapeutics
@en
Going beyond the liver: progre ...... delivery of siRNA therapeutics
@nl
P2093
P3181
P1476
Going beyond the liver: progre ...... delivery of siRNA therapeutics
@en
P2093
Anna-Maria Winkler
Cornelia Lorenzer
Johannes Winkler
Mehrdad Dirin
Volker Baumann
P3181
P356
10.1016/J.JCONREL.2015.02.003
P407
P577
2015-04-10T00:00:00Z