Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia
about
Discoidin domain receptors promote α1β1- and α2β1-integrin mediated cell adhesion to collagen by enhancing integrin activationThe primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domainCrystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutationsPlatelet activation and signal transduction by convulxin, a C-type lectin from Crotalus durissus terrificus (tropical rattlesnake) venom via the p62/GPVI collagen receptorMembrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human plateletsA patient with platelets deficient in glycoprotein VI that lack both collagen-induced aggregation and adhesionMicrofluidics and coagulation biologyPrimary arrest of circulating platelets on collagen involves phosphorylation of Syk, cortactin and focal adhesion kinase: studies under flow conditionsA PLC gamma 2-independent platelet collagen aggregation requiring functional association of GPVI and integrin alpha2beta1Analysis of the interaction of platelet collagen receptor glycoprotein VI (GPVI) with collagen. A dimeric form of GPVI, but not the monomeric form, shows affinity to fibrous collagenGlycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen.Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogenHigh-speed platelet adhesion under conditions of rapid flow.Association of integrin alpha2 gene variants with ischemic strokeSynthesis of heterotrimeric collagen peptides containing the alpha1beta1 integrin recognition site of collagen type IV.A consensus tetrapeptide selected by phage display adopts the conformation of a dominant discontinuous epitope of a monoclonal anti-VWF antibody that inhibits the von Willebrand factor-collagen interaction.Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa (GPIa/IIa, Integrin alpha 2beta 1). Involvement of GPIa/IIa-associated src and protein tyrosine phosphorylation.alpha 2beta 1 integrin is not recognized by rhodocytin but is the specific, high affinity target of rhodocetin, an RGD-independent disintegrin and potent inhibitor of cell adhesion to collagen.Evidence that adhesion of electrically permeabilized platelets to collagen is mediated by guanine nucleotide regulatory proteinsCytosolic calcium as a second messenger for collagen-induced platelet responses.Immunochemical characterization of the new platelet alloantigen system Bra/Brb.Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketoneReview article: platelet-collagen interactions: membrane receptors and intracellular signalling pathways.Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice.The human platelet alloantigens Br(a) and Brb are associated with a single amino acid polymorphism on glycoprotein Ia (integrin subunit alpha 2)Increased platelet deposition on atherosclerotic coronary arteriesArginine-glycine-aspartic acid- and fibrinogen gamma-chain carboxyterminal peptides inhibit platelet adherence to arterial subendothelium at high wall shear rates. An effect dissociable from interference with adhesive protein binding.The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others.A 3D matrix platform for the rapid generation of therapeutic anti-human carcinoma monoclonal antibodies.Platelet glycoprotein gene polymorphisms and risk of thrombosis: facts and fancies.Platelet proteome changes associated with diabetes and during platelet storage for transfusion.Antigenic polymorphism of human very late activation protein-2 (platelet glycoprotein Ia-IIa). Platelet alloantigen HcaPlatelet adhesion under flow.Platelet receptors and their role in diseases.Glycoprotein Ia C807T gene polymorphism and increased risk of recurrent acute coronary syndromes: a five year follow up.The alpha(2) integrin subunit-deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis.Extracellular matrix proteins in hemostasis and thrombosisIdentification of a membrane skeleton in platelets.Integrin heterodimer and receptor complexity in avian and mammalian cells.Incidence and risk factors of bleeding-related adverse events in patients with chronic lymphocytic leukemia treated with ibrutinib.
P2860
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P2860
Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia
description
2016 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2016
@ast
scientific journal article
@en
vedecký článok (publikovaný 2016/12/05)
@sk
vědecký článek publikovaný v roce 2016
@cs
wetenschappelijk artikel (gepubliceerd op 2016/12/05)
@nl
наукова стаття, опублікована в грудні 2016
@uk
مقالة علمية (نشرت في 5-12-2016)
@ar
name
Human blood platelets showing ...... xpress surface glycoprotein Ia
@ast
Human blood platelets showing ...... xpress surface glycoprotein Ia
@en
Human blood platelets showing ...... xpress surface glycoprotein Ia
@nl
type
label
Human blood platelets showing ...... xpress surface glycoprotein Ia
@ast
Human blood platelets showing ...... xpress surface glycoprotein Ia
@en
Human blood platelets showing ...... xpress surface glycoprotein Ia
@nl
prefLabel
Human blood platelets showing ...... xpress surface glycoprotein Ia
@ast
Human blood platelets showing ...... xpress surface glycoprotein Ia
@en
Human blood platelets showing ...... xpress surface glycoprotein Ia
@nl
P2093
P356
P1433
P1476
Human blood platelets showing ...... xpress surface glycoprotein Ia
@en
P2093
H. K. Nieuwenhuis
J. J. Sixma
J. W. Akkerman
W. P. Houdijk
P2888
P304
P356
10.1038/318470A0
P407
P577
2016-12-05T00:00:00Z
P6179
1028319662