ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
about
DNA IR-Double Strand Breaks (DSBs) and cellular response via ATMThe evolution of function within the Nudix homology clan.PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes.Use of luciferase probes to measure ATP in living cells and animals.Insight into the machinery that oils chromatin dynamics.Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.Metabolic Dysfunction in Parkinson's Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism.2-Oxoadenosine induces cytotoxicity through intracellular accumulation of 2-oxo-ATP and depletion of ATP but not via the p38 MAPK pathwaySteroid hormone receptors silence genes by a chromatin-targeted mechanism similar to those used for gene activation.The metabolic enzyme fructose-1,6-bisphosphate aldolase acts as a transcriptional regulator in pathogenic Francisella.MutT-related proteins are novel progression and prognostic markers for colorectal cancer.A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family.The role of poly ADP-ribosylation in the first wave of DNA damage response.Transcriptional precision and accuracy in development: from measurements to models and mechanisms.Signaling by Steroid Hormones in the 3D Nuclear Space.Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.PARP-1-dependent recruitment of cold-inducible RNA-binding protein promotes double-strand break repair and genome stability.A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers.Dual roles for ATP in the regulation of phase separated protein aggregates in oocyte nucleoliThe MacroH2A1.1 - PARP1 Axis at the Intersection Between Stress Response and Metabolism
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ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
description
2016 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2016
@ast
im Juni 2016 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2016/06/03)
@sk
vědecký článek publikovaný v roce 2016
@cs
wetenschappelijk artikel (gepubliceerd op 2016/06/03)
@nl
наукова стаття, опублікована в червні 2016
@uk
name
ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
@ast
ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
@en
ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
@nl
type
label
ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
@ast
ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
@en
ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
@nl
prefLabel
ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
@ast
ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
@en
ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
@nl
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P50
P921
P356
P1433
P1476
ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
@en
P2093
Antonios Lioutas
Baldo Oliva
Constanze Schelhorn
Daniel Soronellas
Francois Le Dily
Michael Wierer
Miguel Beato
Miriam A Trabado
P2860
P304
P356
10.1126/SCIENCE.AAD9335
P407
P50
P577
2016-06-01T00:00:00Z