Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule
about
ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.Specific activation of leukocyte beta2 integrins lymphocyte function-associated antigen-1 and Mac-1 by chemokines mediated by distinct pathways via the alpha subunit cytoplasmic domainsSimilarities in function and gene structure of cytohesin-4 and cytohesin-1, guanine nucleotide-exchange proteins for ADP-ribosylation factorsPRELI, the human homologue of the avian px19, is expressed by germinal center B lymphocytesPhosphorylated pleckstrin induces cell spreading via an integrin-dependent pathwayCloning of ACP33 as a novel intracellular ligand of CD4Regulation of CD40 and CD40 ligand by the AT-hook transcription factor AKNACybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity.Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagementVital function of PRELI and essential requirement of its LEA motifAttenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestrationICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrinFilamin binds to the cytoplasmic domain of the beta1-integrin. Identification of amino acids responsible for this interactionCalcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteinsNerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homologyARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factorsCytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP-ribosylation factorARNO3, a Sec7-domain guanine nucleotide exchange factor for ADP ribosylation factor 1, is involved in the control of Golgi structure and functionA novel function for the Tec family tyrosine kinase Itk in activation of beta 1 integrins by the T-cell receptorGEP100/BRAG2: activator of ADP-ribosylation factor 6 for regulation of cell adhesion and actin cytoskeleton via E-cadherin and alpha-cateninThe PH domain and the polybasic c domain of cytohesin-1 cooperate specifically in plasma membrane association and cellular functionDifferent splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunitsThe ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1Solution structure of the cytohesin-1 (B2-1) Sec7 domain and its interaction with the GTPase ADP ribosylation factor 1A novel B lymphocyte-associated adaptor protein, Bam32, regulates antigen receptor signaling downstream of phosphatidylinositol 3-kinaseRegulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activationEnhancement of endothelial cell migration and in vitro tube formation by TAP20, a novel beta 5 integrin-modulating, PKC theta-dependent proteinPhosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinaseAffinity modulation of platelet integrin alphaIIbbeta3 by beta3-endonexin, a selective binding partner of the beta3 integrin cytoplasmic tailCytohesin-1 regulates beta-2 integrin-mediated adhesion through both ARF-GEF function and interaction with LFA-1Identification of a novel Rev-interacting cellular protein.The guanine nucleotide exchange factor ARNO mediates the activation of ARF and phospholipase D by insulin.Research advances on structure and biological functions of integrinsLeukocyte integrins: role in leukocyte recruitment and as therapeutic targets in inflammatory diseaseRegulators and Effectors of Arf GTPases in NeutrophilsStructure of the Sec7 domain of the Arf exchange factor ARNOBrefeldin A-inhibited guanine nucleotide-exchange activity of Sec7 domain from yeast Sec7 with yeast and mammalian ADP ribosylation factors.The ADP-ribosylation factor (ARF)-related GTPase ARF-related protein binds to the ARF-specific guanine nucleotide exchange factor cytohesin and inhibits the ARF-dependent activation of phospholipase DSpecific functional interaction of human cytohesin-1 and ADP-ribosylation factor domain protein (ARD1)
P2860
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P2860
Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule
description
1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1996
@ast
im Juli 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/07/26)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/07/26)
@nl
наукова стаття, опублікована в липні 1996
@uk
научни чланак (објављен 1996/07/26)
@sr
name
Alpha L beta 2 integrin/LFA-1 ...... ytoplasmic regulatory molecule
@ast
Alpha L beta 2 integrin/LFA-1 ...... ytoplasmic regulatory molecule
@en
Alpha L beta 2 integrin/LFA-1 ...... ytoplasmic regulatory molecule
@nl
type
label
Alpha L beta 2 integrin/LFA-1 ...... ytoplasmic regulatory molecule
@ast
Alpha L beta 2 integrin/LFA-1 ...... ytoplasmic regulatory molecule
@en
Alpha L beta 2 integrin/LFA-1 ...... ytoplasmic regulatory molecule
@nl
prefLabel
Alpha L beta 2 integrin/LFA-1 ...... ytoplasmic regulatory molecule
@ast
Alpha L beta 2 integrin/LFA-1 ...... ytoplasmic regulatory molecule
@en
Alpha L beta 2 integrin/LFA-1 ...... ytoplasmic regulatory molecule
@nl
P2093
P3181
P1433
P1476
Alpha L beta 2 integrin/LFA-1 ...... ytoplasmic regulatory molecule
@en
P2093
P304
P3181
P356
10.1016/S0092-8674(00)80095-1
P407
P577
1996-07-01T00:00:00Z