RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication
about
TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwindingGetting Ready for the Dance: FANCJ Irons Out DNA WrinklesG-quadruplexes and helicasesG-quadruplexes and their regulatory roles in biologyMolecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndromeRTEL1 (regulator of telomere elongation helicase 1), a DNA helicase essential for genome stabilityAssociation between RTEL1 gene polymorphisms and COPD susceptibility in a Chinese Han populationVariants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.TopoIIα prevents telomere fragility and formation of ultra thin DNA bridges during mitosis through TRF1-dependent binding to telomeresClinical and Molecular Heterogeneity of RTEL1 DeficiencyDifferential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats.Rad51 regulates cell cycle progression by preserving G2/M transition in mouse embryonic stem cells.Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a complex telomere biology disorderTelomere stability and development of ctc1 mutants are rescued by inhibition of EJ recombination pathways in a telomerase-dependent manner.TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.Human regulator of telomere elongation helicase 1 (RTEL1) is required for the nuclear and cytoplasmic trafficking of pre-U2 RNA.Association between regulator of telomere elongation helicase 1 polymorphism and susceptibility to glioma.Rare variants in RTEL1 are associated with familial interstitial pneumoniaRepeat instability during DNA repair: Insights from model systemsIdentification of telomere dysfunction in Friedreich ataxiaG4-associated human diseases.Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis.Human CST abundance determines recovery from diverse forms of DNA damage and replication stress.Complex interactions between the DNA-damage response and mammalian telomeres.The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis.TMPyP4 promotes cancer cell migration at low doses, but induces cell death at high dosesThe molecular genetics of the telomere biology disorders.SMARCAL1 Resolves Replication Stress at ALT Telomeres.Structure-function analysis of DNA helicase HELQ: A new diagnostic marker in ovarian cancer.Stop pulling my strings - what telomeres taught us about the DNA damage response.G-quadruplex interacting small molecules and drugs: from bench toward bedside.How homologous recombination maintains telomere integrity.The role of the RTEL1 rs2297440 polymorphism in the risk of glioma development: a meta-analysis.Characterization of the 5'-flanking region of the human DNA helicase B (HELB) gene and its response to trans-Resveratrol.Elevated levels of TRF2 induce telomeric ultrafine anaphase bridges and rapid telomere deletions.Mammalian telomeres and their partnership with lamins.Getting it done at the ends: Pif1 family DNA helicases and telomeres.Mechanistic and biological considerations of oxidatively damaged DNA for helicase-dependent pathways of nucleic acid metabolism.Solving the Telomere Replication Problem.Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork.
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P2860
RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication
description
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2013
@ast
im Oktober 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/10/11)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/10/11)
@nl
наукова стаття, опублікована в жовтні 2013
@uk
name
RTEL1 is a replisome-associate ...... re and genome-wide replication
@ast
RTEL1 is a replisome-associate ...... re and genome-wide replication
@en
RTEL1 is a replisome-associate ...... re and genome-wide replication
@nl
type
label
RTEL1 is a replisome-associate ...... re and genome-wide replication
@ast
RTEL1 is a replisome-associate ...... re and genome-wide replication
@en
RTEL1 is a replisome-associate ...... re and genome-wide replication
@nl
prefLabel
RTEL1 is a replisome-associate ...... re and genome-wide replication
@ast
RTEL1 is a replisome-associate ...... re and genome-wide replication
@en
RTEL1 is a replisome-associate ...... re and genome-wide replication
@nl
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RTEL1 is a replisome-associate ...... re and genome-wide replication
@en
P2093
Simon J Boulton
Sumit Sandhu
Zinnatun Nabi
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P304
P3181
P356
10.1126/SCIENCE.1241779
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P577
2013-10-01T00:00:00Z