Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein
about
Cdx4 and menin co-regulate Hoxa9 expression in hematopoietic cellsMirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alphaThe HOXC11 homeodomain protein interacts with the lactase-phlorizin hydrolase promoter and stimulates HNF1alpha-dependent transcriptionTetrahydrobiopterin biosynthesis, regeneration and functionsHyperphenylalaninemia with high levels of 7-biopterin is associated with mutations in the PCBD gene encoding the bifunctional protein pterin-4a-carbinolamine dehydratase and transcriptional coactivator (DCoH).The bifunctional DCOH protein binds to HNF1 independently of its 4-alpha-carbinolamine dehydratase activityMore potent transcriptional activators or a transdominant inhibitor of the HNF1 homeoprotein family are generated by alternative RNA processingStudies on the enzymatic and transcriptional activity of the dimerization cofactor for hepatocyte nuclear factor 1Mutation in the 4a-carbinolamine dehydratase gene leads to mild hyperphenylalaninemia with defective cofactor metabolismComputational analysis of tissue-specific combinatorial gene regulation: predicting interaction between transcription factors in human tissuesHeat-shock mediated overexpression of HNF1β mutations has differential effects on gene expression in the Xenopus pronephric kidneyNuclear factors are involved in hepatitis C virus RNA replicationThree-dimensional structure of the bifunctional protein PCD/DCoH, a cytoplasmic enzyme interacting with transcription factor HNF1A novel transcriptional activator originating from an upstream promoter in human growth hormone geneCloning of the human claudin-2 5'-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1alphaBerry Phenolic Compounds Increase Expression of Hepatocyte Nuclear Factor-1α (HNF-1α) in Caco-2 and Normal Colon Cells Due to High Affinities with Transcription and Dimerization Domains of HNF-1αCharacterization of the wild-type form of 4a-carbinolamine dehydratase and two naturally occurring mutants associated with hyperphenylalaninemiaStructure and function of PCD/DCoH, an enzyme with regulatory propertiesDimerization co-factor of hepatocyte nuclear factor 1/pterin-4alpha-carbinolamine dehydratase is necessary for pigmentation in Xenopus and overexpressed in primary human melanoma lesionsCircadian periodicity of intestinal Na+/glucose cotransporter 1 mRNA levels is transcriptionally regulatedLFB1/HNF1 acts as a repressor of its own transcriptionVitamin D-binding protein gene transcription is regulated by the relative abundance of hepatocyte nuclear factors 1alpha and 1betaHox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox clusterIdentity of 4a-carbinolamine dehydratase, a component of the phenylalanine hydroxylation system, and DCoH, a transregulator of homeodomain proteinsIdentification and properties of the RNA-dependent RNA polymerase of hepatitis C virusHuman enhancer of rudimentary is a molecular partner of PDIP46/SKAR, a protein interacting with DNA polymerase delta and S6K1 and regulating cell growth.Hepatocyte nuclear factor 1 and hypertensive nephropathy.Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha.An antiestrogen: a phosphotyrosyl peptide that blocks dimerization of the human estrogen receptor.Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter.The transcriptional activator Mirk/Dyrk1B is sequestered by p38alpha/beta MAP kinase.Epstein-barr virus-induced changes in B-lymphocyte gene expression.Regulation of albumin gene expression in hepatoma cells of fetal phenotype: dominant inhibition of HNF1 function and role of ubiquitous transcription factorsRegulation of HSulf-1 expression by variant hepatic nuclear factor 1 in ovarian cancer.Diabetes-associated mutations in a beta-cell transcription factor destabilize an antiparallel "mini-zipper" in a dimerization interface.Interactions with the bifunctional interface of the transcriptional coactivator DCoH1 are kinetically regulated.Overexpression of pterin-4a-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 in human colon cancer.Identification of hepatic nuclear factor 1 binding sites in the 5' flanking region of the human phenylalanine hydroxylase gene: implication of a dual function of phenylalanine hydroxylase stimulator in the phenylalanine hydroxylation system.Expression of hepatic transcription factors during liver development and oval cell differentiation.Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus.
P2860
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P248
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P2860
Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein
description
1991 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 1991
@ast
im Dezember 1991 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1991/12/20)
@sk
vědecký článek publikovaný v roce 1991
@cs
wetenschappelijk artikel (gepubliceerd op 1991/12/20)
@nl
наукова стаття, опублікована в грудні 1991
@uk
name
Characterization of a cofactor ...... mammalian homeodomain protein
@ast
Characterization of a cofactor ...... mammalian homeodomain protein
@en
Characterization of a cofactor ...... mammalian homeodomain protein
@nl
type
label
Characterization of a cofactor ...... mammalian homeodomain protein
@ast
Characterization of a cofactor ...... mammalian homeodomain protein
@en
Characterization of a cofactor ...... mammalian homeodomain protein
@nl
prefLabel
Characterization of a cofactor ...... mammalian homeodomain protein
@ast
Characterization of a cofactor ...... mammalian homeodomain protein
@en
Characterization of a cofactor ...... mammalian homeodomain protein
@nl
P2093
P3181
P356
P1433
P1476
Characterization of a cofactor ...... mammalian homeodomain protein
@en
P2093
D. B. Mendel
G. R. Crabtree
L. P. Hansen
M. K. Graves
P. A. Khavari
P. B. Conley
P304
P3181
P356
10.1126/SCIENCE.1763325
P407
P577
1991-12-20T00:00:00Z