Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP
about
Gamete activation: basic knowledge and clinical applications"This is where it all started" - the pivotal role of PLCζ within the sophisticated process of mammalian reproduction: a systemic review.PLCζ sequence, protein levels, and distribution in human sperm do not correlate with semen characteristics and fertilization rates after ICSIAntigen unmasking enhances visualization efficacy of the oocyte activation factor, phospholipase C zeta, in mammalian sperm.Oocyte Activation and Fertilisation: Crucial Contributors from the Sperm and Oocyte.Whole-exome sequencing of familial cases of multiple morphological abnormalities of the sperm flagella (MMAF) reveals new DNAH1 mutations.Calcium influx and sperm-evoked calcium responses during oocyte maturation and egg activation.PLCζ is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence.WBP2NL/PAWP mRNA and protein expression in sperm cells are not related to semen parameters, fertilization rate, or reproductive outcome.A novel mutation in the TUBB8 gene is associated with complete cleavage failure in fertilized eggs.
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P2860
Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP
description
2016 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2016
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im März 2016 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2016/03/01)
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vědecký článek publikovaný v roce 2016
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wetenschappelijk artikel (gepubliceerd op 2016/03/01)
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наукова стаття, опублікована в березні 2016
@uk
مقالة علمية (نشرت في مارس 2016)
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name
Homozygous mutation of PLCZ1 l ...... by the WW-binding protein PAWP
@ast
Homozygous mutation of PLCZ1 l ...... by the WW-binding protein PAWP
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Homozygous mutation of PLCZ1 l ...... by the WW-binding protein PAWP
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type
label
Homozygous mutation of PLCZ1 l ...... by the WW-binding protein PAWP
@ast
Homozygous mutation of PLCZ1 l ...... by the WW-binding protein PAWP
@en
Homozygous mutation of PLCZ1 l ...... by the WW-binding protein PAWP
@nl
prefLabel
Homozygous mutation of PLCZ1 l ...... by the WW-binding protein PAWP
@ast
Homozygous mutation of PLCZ1 l ...... by the WW-binding protein PAWP
@en
Homozygous mutation of PLCZ1 l ...... by the WW-binding protein PAWP
@nl
P2093
P2860
P50
P3181
P356
P1476
Homozygous mutation of PLCZ1 l ...... by the WW-binding protein PAWP
@en
P2093
Chema Triki
Hoi Chang Lee
Lazhar Halouani
Rafael Fissore
Raoudha Zouari
Sandra Yassine
Sergey N Savinov
Thomas Karaouzène
P2860
P304
P3181
P356
10.1093/HMG/DDV617
P50
P577
2015-12-31T00:00:00Z