Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.
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Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast CancerMediator kinase module and human tumorigenesisThe Mediator complex and transcription regulationAnalysis of Candida albicans mutants defective in the Cdk8 module of mediator reveal links between metabolism and biofilm formationOncogenic senescence: a multi-functional perspective.SEL120-34A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domainsTargeting cell cycle regulators in hematologic malignancies.Retroviral cyclin controls cyclin-dependent kinase 8-mediated transcription elongation and reinitiation.Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cellsSkp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis.A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators.Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblastsA selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence.Improving Pathological Assessment of Breast Cancer by Employing Array-Based Transcriptome Analysis.Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A.Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer.Functional states of resident vascular stem cells and vascular remodeling.Matters of context guide future research in TGFβ superfamily signaling.Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells.Cdk8 deletion in the Apc(Min) murine tumour model represses EZH2 activity and accelerates tumourigenesis.Mediator complex cooperatively regulates transcription of retinoic acid target genes with Polycomb Repressive Complex 2 during neuronal differentiation.bHLH proteins involved in Drosophila neurogenesis are mutually regulated at the level of stabilityInvestigational drugs targeting cyclin-dependent kinases for the treatment of cancer: an update on recent findings (2013-2016).Inhibitors of cyclin-dependent kinases as cancer therapeutics.CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells.Regulation of the human papillomavirus type 16 late promoter by transcriptional elongation.CDK8: a new breast cancer target.2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19.Ciclopirox enhances pancreatic islet health by modulating the unfolded protein response in diabetes.CDK8 Kinase Activity Promotes Glycolysis.MED12 mutations and NOTCH signalling in chronic lymphocytic leukaemia.Growth of human breast cancers in Peromyscus.CDK8/19 inhibition induces premature G1/S transition and ATR-dependent cell death in prostate cancer cells.
P2860
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P2860
Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Cyclin-dependent kinase 8 medi ...... promoting paracrine activities
@nl
Cyclin-dependent kinase 8 medi ...... romoting paracrine activities.
@ast
Cyclin-dependent kinase 8 medi ...... romoting paracrine activities.
@en
type
label
Cyclin-dependent kinase 8 medi ...... promoting paracrine activities
@nl
Cyclin-dependent kinase 8 medi ...... romoting paracrine activities.
@ast
Cyclin-dependent kinase 8 medi ...... romoting paracrine activities.
@en
prefLabel
Cyclin-dependent kinase 8 medi ...... promoting paracrine activities
@nl
Cyclin-dependent kinase 8 medi ...... romoting paracrine activities.
@ast
Cyclin-dependent kinase 8 medi ...... romoting paracrine activities.
@en
P2093
P2860
P921
P356
P1476
Cyclin-dependent kinase 8 medi ...... promoting paracrine activities
@en
P2093
Anatoliy T Puzyrev
Athanasios G Papavassiliou
Bey-Dih Chang
Chang-uk Lim
Deborah K West
Donald C Porter
Elena Farmaki
Eugenia V Broude
Gary P Schools
Gregory Hurteau
P2860
P304
13799-13804
P356
10.1073/PNAS.1206906109
P407
P577
2012-08-06T00:00:00Z