TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway
about
Phosphatidylserine-targeting antibodies augment the anti-tumorigenic activity of anti-PD-1 therapy by enhancing immune activation and downregulating pro-oncogenic factors induced by T-cell checkpoint inhibition in murine triple-negative breast canceHigh Expression of Antiviral and Vitamin D Pathway Genes Are a Natural Characteristic of a Small Cohort of HIV-1-Exposed Seronegative Individuals.TIM-3 as a Target for Cancer Immunotherapy and Mechanisms of Action.Inhibitory Receptors Induced by VSV Viroimmunotherapy Are Not Necessarily Targets for Improving Treatment Efficacy.A cellular platform for the evaluation of immune checkpoint molecules.Atorvastatin downregulates co-inhibitory receptor expression by targeting Ras-activated mTOR signalling.TIM-3 Engagement Promotes Effector Memory T Cell Differentiation of Human Antigen-Specific CD8 T Cells by Activating mTORC1.Acute Stimulation Generates Tim-3-expressing Th1-type CD4 T Cells That Persist In Vivo and Show Enhanced Effector Function.Not All Immune Checkpoints Are Created Equal
P2860
Q36895458-78A170EF-5621-4C5B-A07A-68F4DE23E39EQ37637890-8A5CA90D-7457-4816-855D-C1F5F767F3C9Q37729313-CD1021DE-0619-4334-BBFB-DEC86CFFE1C1Q38941936-9D09D860-A866-459B-BB24-D57A67213850Q42371484-E4AB8694-A9CA-4037-A903-A06D301B4DB5Q47125276-D1190B74-7411-4BFF-9E5C-A7462890768AQ47133354-D74B9A94-D52E-40E7-8D45-DE35189F2C3BQ47556597-8762A4FD-87E5-452C-B8C0-8ECA401751B9Q56889626-6B8F4F52-DE17-4545-8B29-8F2F18C3A837
P2860
TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway
description
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique PLoS ONE
@fr
artikull shkencor
@sq
artículu científicu espublizáu en 2015
@ast
im Januar 2015 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2015
@uk
مقالة علمية (نشرت عام 2015)
@ar
name
TIM-3 Suppresses Anti-CD3/CD28 ...... ugh the NFAT Signaling Pathway
@ast
TIM-3 Suppresses Anti-CD3/CD28 ...... ugh the NFAT Signaling Pathway
@en
TIM-3 Suppresses Anti-CD3/CD28 ...... ugh the NFAT Signaling Pathway
@nl
type
label
TIM-3 Suppresses Anti-CD3/CD28 ...... ugh the NFAT Signaling Pathway
@ast
TIM-3 Suppresses Anti-CD3/CD28 ...... ugh the NFAT Signaling Pathway
@en
TIM-3 Suppresses Anti-CD3/CD28 ...... ugh the NFAT Signaling Pathway
@nl
prefLabel
TIM-3 Suppresses Anti-CD3/CD28 ...... ugh the NFAT Signaling Pathway
@ast
TIM-3 Suppresses Anti-CD3/CD28 ...... ugh the NFAT Signaling Pathway
@en
TIM-3 Suppresses Anti-CD3/CD28 ...... ugh the NFAT Signaling Pathway
@nl
P2093
P2860
P3181
P1433
P1476
TIM-3 Suppresses Anti-CD3/CD28 ...... ugh the NFAT Signaling Pathway
@en
P2093
Brian Tomkowicz
Chen-Ni Chin
Eileen Walsh
Fred Kaplan
Jill Mooney
Michael Naso
Nina Sabins
Raluca Verona
Russell B Lingham
Sandy Santulli-Marotto
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0140694
P407
P50
P577
2015-01-01T00:00:00Z