Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies
about
Hereditary Predispositions to Myelodysplastic SyndromeThe genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemiaAberrant RNA splicing and mutations in spliceosome complex in acute myeloid leukemia.Evaluation of Patients and Families With Concern for Predispositions to Hematologic Malignancies Within the Hereditary Hematologic Malignancy Clinic (HHMC).Germline heterozygous DDX41 variants in a subset of familial myelodysplasia and acute myeloid leukemia.The emerging roles of the DDX41 protein in immunity and diseases.Mechanisms of Immune Tolerance in Leukemia and Lymphoma.The DEAD-box RNA helicase DDX41 is a novel repressor of p21WAF1/CIP1 mRNA translation.Turning the tide in myelodysplastic/myeloproliferative neoplasms.The expanding regulatory network of STING-mediated signaling.Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists.Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis.Germline Genetic Predisposition to Hematologic Malignancy.Myeloid neoplasms with germline DDX41 mutation.Familial Myelodysplastic/Acute Leukemia Syndromes-Myeloid Neoplasms with Germline PredispositionTwo novel germline DDX41 mutations in a family with inherited myelodysplasia/acute myeloid leukemia.Diagnostics and Prognostication of Myelodysplastic Syndromes.Identification of host DEAD-box RNA helicases that regulate cellular tropism of oncolytic Myxoma virus in human cancer cells.Clinical Assessment and Diagnosis of Germline Predisposition to Hematopoietic Malignancies: The University of Chicago Experience.Familial predisposition of myeloid malignancies: biological and clinical significance of recurrent germ line mutations.Re-emergence of acute myeloid leukemia in donor cells following allogeneic transplantation in a family with a germline DDX41 mutation.Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes.How I diagnose and manage individuals at risk for inherited myeloid malignancies.DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection.Identification of DEAD-Box RNA Helicase DDX41 as a Trafficking Protein That Involves in Multiple Innate Immune Signaling Pathways in a Zebrafish Model.Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies
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P2860
Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies
description
2016 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2016
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im Februar 2016 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2016/02/25)
@sk
vědecký článek publikovaný v roce 2016
@cs
wetenschappelijk artikel (gepubliceerd op 2016/02/25)
@nl
наукова стаття, опублікована в лютому 2016
@uk
مقالة علمية (نشرت في 25-2-2016)
@ar
name
Novel germ line DDX41 mutation ...... nset and lymphoid malignancies
@ast
Novel germ line DDX41 mutation ...... nset and lymphoid malignancies
@en
Novel germ line DDX41 mutation ...... nset and lymphoid malignancies
@nl
type
label
Novel germ line DDX41 mutation ...... nset and lymphoid malignancies
@ast
Novel germ line DDX41 mutation ...... nset and lymphoid malignancies
@en
Novel germ line DDX41 mutation ...... nset and lymphoid malignancies
@nl
prefLabel
Novel germ line DDX41 mutation ...... nset and lymphoid malignancies
@ast
Novel germ line DDX41 mutation ...... nset and lymphoid malignancies
@en
Novel germ line DDX41 mutation ...... nset and lymphoid malignancies
@nl
P2093
P2860
P50
P3181
P1433
P1476
Novel germ line DDX41 mutation ...... nset and lymphoid malignancies
@en
P2093
Akiko Shimamura
Bruno C Medeiros
Connie Phung
Daniel A Pollyea
George Rafidi
Graeme K Suthers
Ian D Lewis
Jane E Churpek
Jinghua Feng
Kerry Phillips
P2860
P304
P3181
P356
10.1182/BLOOD-2015-10-676098
P407
P50
P577
2016-02-25T00:00:00Z