Complete rescue of lethal albino c14CoS mice by null mutation of 4-hydroxyphenylpyruvate dioxygenase and induction of apoptosis of hepatocytes in these mice by in vivo retrieval of the tyrosine catabolic pathway
about
Mechanistic inferences from the crystal structure of fumarylacetoacetate hydrolase with a bound phosphorus-based inhibitorA universal system to select gene-modified hepatocytes in vivoskn-1-Dependent and -independent regulation of aip-1 expression following metabolic stress in Caenorhabditis elegans.Hereditary tyrosinaemia type I: from basics to progress in treatment.Maleylacetoacetate isomerase (MAAI/GSTZ)-deficient mice reveal a glutathione-dependent nonenzymatic bypass in tyrosine catabolism.In vivo suppressor mutations correct a murine model of hereditary tyrosinemia type I.Aneuploidy as a mechanism for stress-induced liver adaptation.Hepatocyte injury in tyrosinemia type 1 is induced by fumarylacetoacetate and is inhibited by caspase inhibitors.Genome editing for inborn errors of metabolism: advancing towards the clinic.In vivo selection of transplanted hepatocytes by pharmacological inhibition of fumarylacetoacetate hydrolase in wild-type miceThe Caenorhabditis elegans K10C2.4 gene encodes a member of the fumarylacetoacetate hydrolase family: a Caenorhabditis elegans model of type I tyrosinemia.Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemiaValidation of a multi-omics strategy for prioritizing personalized candidate driver genesCRISPR/Cas9: at the cutting edge of hepatology.Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.Heat shock response associated with hepatocarcinogenesis in a murine model of hereditary tyrosinemia type I.High volume naked DNA tail-vein injection restores liver function in Fah-knock out mice.A potential biomarker of kidney damage identified by proteomics: preliminary findings.NTBC and Correction of Renal Dysfunction.
P2860
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P2860
Complete rescue of lethal albino c14CoS mice by null mutation of 4-hydroxyphenylpyruvate dioxygenase and induction of apoptosis of hepatocytes in these mice by in vivo retrieval of the tyrosine catabolic pathway
description
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1997
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im September 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/09/26)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/09/26)
@nl
наукова стаття, опублікована у вересні 1997
@uk
name
Complete rescue of lethal albi ...... the tyrosine catabolic pathway
@ast
Complete rescue of lethal albi ...... the tyrosine catabolic pathway
@en
Complete rescue of lethal albi ...... the tyrosine catabolic pathway
@nl
type
label
Complete rescue of lethal albi ...... the tyrosine catabolic pathway
@ast
Complete rescue of lethal albi ...... the tyrosine catabolic pathway
@en
Complete rescue of lethal albi ...... the tyrosine catabolic pathway
@nl
prefLabel
Complete rescue of lethal albi ...... the tyrosine catabolic pathway
@ast
Complete rescue of lethal albi ...... the tyrosine catabolic pathway
@en
Complete rescue of lethal albi ...... the tyrosine catabolic pathway
@nl
P2093
P2860
P3181
P356
P1476
Complete rescue of lethal albi ...... the tyrosine catabolic pathway
@en
P2093
I. Matsuda
J. Miyazaki
S. Hattori
P2860
P304
24426–24432
P3181
P356
10.1074/JBC.272.39.24426
P407
P577
1997-09-26T00:00:00Z