Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway
about
Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitorPim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XLThe 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cellsThe 44 kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugsPIM-1 kinase interacts with the DNA binding domain of the vitamin D receptor: a further kinase implicated in 1,25-(OH)2D3 signalingPIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersPim1 kinase synergizes with c-MYC to induce advanced prostate carcinomaCryptic promoter activity in the DNA sequence corresponding to the pim-1 5'-UTRTargeting the Pim kinases in multiple myelomaEpstein-Barr Virus: Diseases Linked to Infection and TransformationPAP-1, a novel target protein of phosphorylation by pim-1 kinaseIdentification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)Pim-1 translocates sorting nexin 6/TRAF4-associated factor 2 from cytoplasm to nucleusTargeting Pim kinases for cancer treatment: opportunities and challengesThe PIM kinases in hematological cancersPIM1 kinase as a target for cancer therapyThe oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpointConditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasiaEvidence that the Pim1 kinase gene is a direct target of HOXA9The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitorPim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cellsPhosphorylation site mutations in heterochromatin protein 1 (HP1) reduce or eliminate silencing activity.A single pair of acidic residues in the kinase major groove mediates strong substrate preference for P-2 or P-5 arginine in the AGC, CAMK, and STE kinase families.PIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications.Ki67 and PIM1 expression predict outcome in mantle cell lymphoma treated with high dose therapy, stem cell transplantation and rituximab: a Cancer and Leukemia Group B 59909 correlative science studyPim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity.Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes.In vitro evaluation of dihydropyridine-3-carbonitriles as potential cytotoxic agents through PIM-1 protein kinase inhibition.RNAi screen identifies a synthetic lethal interaction between PIM1 overexpression and PLK1 inhibitionPathophysiological roles of Pim-3 kinase in pancreatic cancer development and progression.Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 functionCell and gene therapy for severe heart failure patients: the time and place for Pim-1 kinase.Regulation of Skp2 levels by the Pim-1 protein kinaseJunD/AP-1-mediated gene expression promotes lymphocyte growth dependent on interleukin-7 signal transduction.Coordinated expression of tristetraprolin post-transcriptionally attenuates mitogenic induction of the oncogenic Ser/Thr kinase Pim-1.Activation of cell cycle arrest and apoptosis by the proto-oncogene Pim-2.Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002.Genomic microarrays: arraying order in biological chaos?Overexpression of Pim-1 in bladder cancer.The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells.
P2860
Q21142745-DDE7F112-695F-4F14-9002-2E7A1501309AQ21284163-3D641B23-EB70-48C0-8B3E-9B85D6B2C6D5Q24302137-56B47141-90BF-4431-997C-55E46EC04B92Q24336934-35C11996-3E59-4208-AA33-6E1B052F35EDQ24338699-CEC0721D-967B-4688-A7F5-9B6462331BFCQ24603099-92A7F023-990E-4E6D-AE9A-D8F040FCFD82Q24630639-E3D49DDF-FE48-4FCB-A08B-94BE66875D1BQ24805890-B8A78219-7B6E-467A-AE9C-A1595DCB7573Q26799499-F880F091-474C-4D2D-8BD1-221BB3BEF0EEQ28074586-F94F6057-B1D7-40AF-8E69-7EC2A640D3B9Q28142891-194A19F4-4E61-4B3B-8A29-854A244189C8Q28144315-C070F47B-2CF9-4CC1-BF47-01661EE7A25CQ28190881-73E65CA2-D2C5-4815-9C2F-D0AE0B8E7530Q28255361-F6446B15-459B-4DDF-A763-AB759C268EC1Q28258028-81B52483-9D19-40A5-AEA3-0E7577A16B1FQ28261162-D81C4DB3-F472-4CD7-8FD6-E8FA5672B710Q28277923-BAE7D52A-88B4-4348-B05E-178A636A2889Q28485913-B3E74B71-E042-4223-9E51-A2B3BC03013AQ28507053-A953F5F5-2CDD-4AA4-8F8E-DCF238DFDF6BQ28508632-D491425E-D375-4B4F-87CD-06A010A45263Q28588864-9B0CE50A-89F2-47BE-9666-D3DFED7ECCE3Q30635763-CCD2A05E-C850-4110-8C7D-058D7D2D68C0Q33222589-0DBB902F-86A7-4827-B2C8-ED6A3DC16176Q33273560-F07EF5F2-F6FE-4C5D-8FE4-A7670D778044Q33572807-3F0B000A-DFA8-4EE0-9B2A-871163C8B913Q33591747-40CD620C-2C2D-4F37-A8E2-1566B1E97826Q33597393-E205FECA-9307-4635-82E1-8491F6DE615AQ33782298-767629D9-4792-4356-81E5-8C460FBE80D9Q33861057-2EC3F9AD-D747-4F7A-BDDC-CB2AA06440A8Q33948355-1A7526AC-5541-47AF-8521-6722D6F09C6FQ33967106-060A2070-E7CD-4C1B-B733-9EE9F2BDECACQ34075071-CDB4E92D-CF22-4E23-B8FE-F7B43E7520ADQ34121488-E87B2DDC-A54B-4C80-BD30-E4364DB89514Q34182432-E3F661C0-EC5D-46F3-AC0E-51E5E33FBA8FQ34193713-A508F173-6918-43E2-8997-A614301F530EQ34233697-C524D30B-1CF3-426E-9D80-E61B8826AD08Q34385592-35C53211-134A-4D63-828F-A95BFA0B300BQ34428506-06C8F8D4-223F-4CA2-8992-9A13A26099CBQ34448018-B2A857C5-98AB-47EC-B62C-151C2A230D00Q34494886-B826A945-22C1-467A-A38D-9FCC41ED71E0
P2860
Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Physical and functional intera ...... of the c-Myc signaling pathway
@ast
Physical and functional intera ...... of the c-Myc signaling pathway
@en
Physical and functional intera ...... of the c-Myc signaling pathway
@nl
type
label
Physical and functional intera ...... of the c-Myc signaling pathway
@ast
Physical and functional intera ...... of the c-Myc signaling pathway
@en
Physical and functional intera ...... of the c-Myc signaling pathway
@nl
prefLabel
Physical and functional intera ...... of the c-Myc signaling pathway
@ast
Physical and functional intera ...... of the c-Myc signaling pathway
@en
Physical and functional intera ...... of the c-Myc signaling pathway
@nl
P2093
P3181
P356
P1476
Physical and functional intera ...... of the c-Myc signaling pathway
@en
P2093
P304
P3181
P356
10.1074/JBC.274.26.18659
P407
P577
1999-06-25T00:00:00Z