Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling
about
MIR16, a putative membrane glycerophosphodiester phosphodiesterase, interacts with RGS16R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1Regulators of G-protein signaling in the heart and their potential as therapeutic targets.Phosphorylation and nuclear translocation of a regulator of G protein signaling (RGS10)Palmitoylation of a conserved cysteine in the regulator of G protein signaling (RGS) domain modulates the GTPase-activating activity of RGS4 and RGS10Palmitoylation regulates regulator of G-protein signaling (RGS) 16 function. II. Palmitoylation of a cysteine residue in the RGS box is critical for RGS16 GTPase accelerating activity and regulation of Gi-coupled signallingPalmitoylation regulates regulators of G-protein signaling (RGS) 16 function. I. Mutation of amino-terminal cysteine residues on RGS16 prevents its targeting to lipid rafts and palmitoylation of an internal cysteine residueRGS16 inhibits signalling through the G alpha 13-Rho axisRGS16 function is regulated by epidermal growth factor receptor-mediated tyrosine phosphorylationSrc-mediated RGS16 tyrosine phosphorylation promotes RGS16 stabilityMultiple phosphorylation sites in RGS16 differentially modulate its GAP activitySmall changes huge impact: the role of protein posttranslational modifications in cellular homeostasis and diseaseMolecular cloning and characterization of a novel regulator of G-protein signaling from mouse hematopoietic stem cellsRegulators of G Protein SignalingThe evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21.Single site alpha-tubulin mutation affects astral microtubules and nuclear positioning during anaphase in Saccharomyces cerevisiae: possible role for palmitoylation of alpha-tubulinRGS4 and RGS5 are in vivo substrates of the N-end rule pathwayDifferential capacities of the RGS1, RGS16 and RGS-GAIP regulators of G protein signaling to enhance alpha2A-adrenoreceptor agonist-stimulated GTPase activity of G(o1)alpha.RGS14 is a bifunctional regulator of Galphai/o activity that exists in multiple populations in brain.Mild heat and proteotoxic stress promote unique subcellular trafficking and nucleolar accumulation of RGS6 and other RGS proteins. Role of the RGS domain in stress-induced trafficking of RGS proteins.Feeding and fasting controls liver expression of a regulator of G protein signaling (Rgs16) in periportal hepatocytesHow regulators of G protein signaling achieve selective regulation.A finer tuning of G-protein signaling through regulated control of RGS proteins.The regulator of G-protein signaling RGS16 promotes insulin secretion and β-cell proliferation in rodent and human islets.GIPC recruits GAIP (RGS19) to attenuate dopamine D2 receptor signaling.Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia.Endoproteolytic processing of Sst2, a multidomain regulator of G protein signaling in yeast.RGS16 restricts the pro-inflammatory response of monocytes.Unique hydrophobic extension of the RGS2 amphipathic helix domain imparts increased plasma membrane binding and function relative to other RGS R4/B subfamily members.Specific induction of RGS16 (regulator of G-protein signalling 16) mRNA by protein kinase C in CEM leukaemia cells is mediated via tumour necrosis factor alpha in a calcium-sensitive manner.The regulator of G protein signaling RGS4 selectively enhances alpha 2A-adreoreceptor stimulation of the GTPase activity of Go1alpha and Gi2alpha.Dependence of RGS9-1 membrane attachment on its C-terminal tail.Differential contribution of GTPase activation and effector antagonism to the inhibitory effect of RGS proteins on Gq-mediated signaling in vivo.RGS3 and RGS4 differentially associate with G protein-coupled receptor-Kir3 channel signaling complexes revealing two modes of RGS modulation. Precoupling and collision coupling.RGS4 binds to membranes through an amphipathic alpha -helix.Regulation of RGS2 and Second Messenger Signaling in Vascular Smooth Muscle Cells by cGMP-dependent Protein Kinase
P2860
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P2860
Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Amino-terminal cysteine residu ...... Gi- and Gq-mediated signaling
@ast
Amino-terminal cysteine residu ...... Gi- and Gq-mediated signaling
@en
Amino-terminal cysteine residu ...... Gi- and Gq-mediated signaling
@nl
type
label
Amino-terminal cysteine residu ...... Gi- and Gq-mediated signaling
@ast
Amino-terminal cysteine residu ...... Gi- and Gq-mediated signaling
@en
Amino-terminal cysteine residu ...... Gi- and Gq-mediated signaling
@nl
prefLabel
Amino-terminal cysteine residu ...... Gi- and Gq-mediated signaling
@ast
Amino-terminal cysteine residu ...... Gi- and Gq-mediated signaling
@en
Amino-terminal cysteine residu ...... Gi- and Gq-mediated signaling
@nl
P2093
P3181
P356
P1476
Amino-terminal cysteine residu ...... Gi- and Gq-mediated signaling
@en
P2093
P304
P3181
P356
10.1074/JBC.274.26.18836
P407
P577
1999-06-25T00:00:00Z