SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis - Wikidata - awgldk - TriplyDB

SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis

SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis

http://www.wikidata.org/entity/Q28138406

about

Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations Hereditary pancreatitis: current perspectives Clinical Genetic Testing in Gastroenterology Framework for interpretation of trypsin-antitrypsin imbalance and genetic heterogeneity in pancreatitis Going MAD: development of a "matrix academic division" to facilitate translating research to personalized medicine Genetics of pancreatitis Chymotrypsin C mutations in chronic pancreatitis.Mutational screening of the cationic trypsinogen gene in a large cohort of subjects with idiopathic chronic pancreatitis Ablation of huntingtin in adult neurons is nondeleterious but its depletion in young mice causes acute pancreatitis.Molecular dynamics simulations reveal structural instability of human trypsin inhibitor upon D50E and Y54H mutations.Role of CCK/gastrin receptors in gastrointestinal/metabolic diseases and results of human studies using gastrin/CCK receptor agonists/antagonists in these diseases.Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.Pathways to injury in chronic pancreatitis: decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis.Connections between genetics and clinical data: Role of MCP-1, CFTR, and SPINK-1 in the setting of acute, acute recurrent, and chronic pancreatitis.American Pancreatic Association Practice Guidelines in Chronic Pancreatitis: evidence-based report on diagnostic guidelines.Inflammation to cancer: The molecular biology in the pancreas (Review).Pancreatitis-associated chymotrypsinogen C (CTRC) mutant elicits endoplasmic reticulum stress in pancreatic acinar cells High Prevalence of Serine Protease Inhibitor Kazal Type 1 Gene Variations Detected by Whole Gene Sequencing in Patients with Fibrocalculous Pancreatic Diabetes.Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway.Lack of association between UGT1A7, UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients.Long-term outcomes of total pancreatectomy and islet auto transplantation for hereditary/genetic pancreatitis.PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis Review of idiopathic pancreatitis Pathophysiology of chronic pancreatitis.Risk factors for pancreatic cancer: underlying mechanisms and potential targets.Genetics of acute and chronic pancreatitis: An update.The prevalence of cationic trypsinogen (PRSS1) and serine protease inhibitor, Kazal type 1 (SPINK1) gene mutations in Polish patients with alcoholic and idiopathic chronic pancreatitis Alcohol and smoking as risk factors in an epidemiology study of patients with chronic pancreatitis.Association of thymidylate synthase polymorphisms with acute pancreatitis and/or peripheral neuropathy in HIV-infected patients on stavudine-based therapy Chronic pancreatitis: Asia-Pacific consensus report.Discovering the route from inflammation to pancreatic cancer.Pancreatic secretory trypsin inhibitor: More than a trypsin inhibitor Chronic pancreatitis and cystic fibrosis.Combined bicarbonate conductance-impairing variants in CFTR and SPINK1 variants are associated with chronic pancreatitis in patients without cystic fibrosis.Are genetic variants in the platelet-derived growth factor [beta] gene associated with chronic pancreatitis?Assessing the pathological relevance of SPINK1 promoter variants.Tropical chronic pancreatitis.

P2860

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P2860

SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis

http://www.wikidata.org/entity/Q28138406

description

2000 nî lūn-bûn

@nan

2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2000年の論文

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2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

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2000年论文

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name

SPINK1/PSTI polymorphisms act ...... diopathic chronic pancreatitis

@ast

SPINK1/PSTI polymorphisms act ...... diopathic chronic pancreatitis

@en

SPINK1/PSTI polymorphisms act ...... diopathic chronic pancreatitis

@nl

type

label

SPINK1/PSTI polymorphisms act ...... diopathic chronic pancreatitis

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SPINK1/PSTI polymorphisms act ...... diopathic chronic pancreatitis

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SPINK1/PSTI polymorphisms act ...... diopathic chronic pancreatitis

@nl

prefLabel

SPINK1/PSTI polymorphisms act ...... diopathic chronic pancreatitis

@ast

SPINK1/PSTI polymorphisms act ...... diopathic chronic pancreatitis

@en

SPINK1/PSTI polymorphisms act ...... diopathic chronic pancreatitis

@nl

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Gastroenterology

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SPINK1/PSTI polymorphisms act ...... diopathic chronic pancreatitis

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A P Brunskill

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D C Whitcomb

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M M Barmada

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2017322

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John P Neoptolemos

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