Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase
about
Human telomerase contains two cooperating telomerase RNA molecules.Specificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivoAn enhanced H/ACA RNP assembly mechanism for human telomerase RNAAnalysis of the structure of human telomerase RNA in vivoHuman telomerase and its regulationCell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeresAllosteric inhibitors of telomerase: oligonucleotide N3'-->P5' phosphoramidatesFinding the end: recruitment of telomerase to telomeresSolution structure and dynamics of the wild-type pseudoknot of human telomerase RNATelomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenitaA human-Tetrahymena pseudoknot chimeric telomerase RNA reconstitutes a nonprocessive enzyme in vitro that is defective in telomere elongationInsertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome MaintenanceIt all comes together at the ends: telomerase structure, function, and biogenesisMutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA.The solution structure of an essential stem-loop of human telomerase RNAYNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA.Structure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNAStructurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNAStructural and functional evidence of high specificity of Cbf5 for ACA trinucleotideStructure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase functionStructural basis for protein-RNA recognition in telomeraseEssential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interactionA bulged stem tethers Est1p to telomerase RNA in budding yeast.Telomerase Regulation from Beginning to the EndStructure of active dimeric human telomerase.Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domainComparative functional study of the viral telomerase RNA based on natural mutationsThe functional requirement of two structural domains within telomerase RNA emerged early in eukaryotesHuman telomerase: biogenesis, trafficking, recruitment, and activation.Template boundary definition in mammalian telomeraseTelomerase structure.Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants.Functional analysis of the pseudoknot structure in human telomerase RNA.Coordinated DNA dynamics during the human telomerase catalytic cycle.Telomerase trafficking and assembly in Xenopus oocytes.RNA binding domain of telomerase reverse transcriptaseA critical stem-loop structure in the CR4-CR5 domain of mammalian telomerase RNA.N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo.The biogenesis and regulation of telomerase holoenzymes
P2860
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P2860
Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase
description
2000 nî lūn-bûn
@nan
2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Human telomerase activation re ...... lomerase reverse transcriptase
@ast
Human telomerase activation re ...... lomerase reverse transcriptase
@en
Human telomerase activation re ...... lomerase reverse transcriptase
@nl
type
label
Human telomerase activation re ...... lomerase reverse transcriptase
@ast
Human telomerase activation re ...... lomerase reverse transcriptase
@en
Human telomerase activation re ...... lomerase reverse transcriptase
@nl
prefLabel
Human telomerase activation re ...... lomerase reverse transcriptase
@ast
Human telomerase activation re ...... lomerase reverse transcriptase
@en
Human telomerase activation re ...... lomerase reverse transcriptase
@nl
P3181
P1433
P1476
Human telomerase activation re ...... lomerase reverse transcriptase
@en
P2093
J R Mitchell
P304
P3181
P356
10.1016/S1097-2765(00)00036-8
P407
P577
2000-08-01T00:00:00Z