Localization of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 pool
about
Phosphorylation of grb10 regulates its interaction with 14-3-3Grb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradationMeaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactionsRole for the adaptor protein Grb10 in the activation of AktA novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and developmentRegulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteinsThe Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functionsTwo novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signalingPhosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II.Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14.Radiation-induced activation of nuclear factor-kappaB involves selective degradation of plasma membrane-associated I(kappa)B(alpha)Mitochondria, aging and longevity--a new perspective.Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: therapeutic perspectivesIn situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interact.Grb10 and Grb14: enigmatic regulators of insulin action--and more?Cardiac mitochondrial matrix and respiratory complex protein phosphorylationFunctional characterization of a mitochondrial Ser/Thr protein phosphatase in cell death regulationFacilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3.Mitochondrial protein phosphorylation as a regulatory modality: implications for mitochondrial dysfunction in heart failure.Grb10 is a dual regulator of receptor tyrosine kinase signaling.FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemiaMEK inhibitors in oncology: a patent review (2015-Present).Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 geneGrb10 and active Raf-1 kinase promote Bad-dependent cell survival.Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action.Anti-apoptotic signaling of the insulin-like growth factor-I receptor through mitochondrial translocation of c-Raf and Nedd4.Grb7 and Hax1 may colocalize partially to mitochondria in EGF-treated SKBR3 cells and their interaction can affect Caspase3 cleavage of Hax1Lentivirus shRNA Grb10 targeting the pancreas induces apoptosis and improved glucose tolerance due to decreased plasma glucagon levels.Plasma membrane localization of Ras requires class C Vps proteins and functional mitochondria in Saccharomyces cerevisiae.Protective role of Raf-1 in Salmonella-induced macrophage apoptosis.Mechanisms by which opening the mitochondrial ATP- sensitive K(+) channel protects the ischemic heart.Rapid identification of dysregulated genes in cutaneous malignant melanoma metastases using cDNA technology.Glypican-3 induces oncogenicity by preventing IGF-1R degradation, a process that can be blocked by Grb10.The adaptors Grb10 and Grb14 are calmodulin-binding proteins.
P2860
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P2860
Localization of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 pool
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Localization of endogenous Grb ...... hondrial-associated Raf-1 pool
@ast
Localization of endogenous Grb ...... hondrial-associated Raf-1 pool
@en
Localization of endogenous Grb ...... hondrial-associated Raf-1 pool
@nl
type
label
Localization of endogenous Grb ...... hondrial-associated Raf-1 pool
@ast
Localization of endogenous Grb ...... hondrial-associated Raf-1 pool
@en
Localization of endogenous Grb ...... hondrial-associated Raf-1 pool
@nl
prefLabel
Localization of endogenous Grb ...... hondrial-associated Raf-1 pool
@ast
Localization of endogenous Grb ...... hondrial-associated Raf-1 pool
@en
Localization of endogenous Grb ...... hondrial-associated Raf-1 pool
@nl
P2860
P356
P1476
Localization of endogenous Grb ...... hondrial-associated Raf-1 pool
@en
P2093
P2860
P304
35719-35724
P356
10.1074/JBC.274.50.35719
P407
P577
1999-12-01T00:00:00Z