Enzymatic action of human glandular kallikrein 2 (hK2). Substrate specificity and regulation by Zn2+ and extracellular protease inhibitors
about
Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14Twenty Years of PSA: From Prostate Antigen to Tumor MarkerEnzymatic action of prostate-specific antigen (PSA or hK3): substrate specificity and regulation by Zn(2+), a tight-binding inhibitorHuman kallikrein-related peptidase 14 (KLK14) is a new activator component of the KLK proteolytic cascade. Possible function in seminal plasma and skinThe emerging roles of human tissue kallikreins in cancerHuman tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progressionExpression and characterization of trypsinogen produced in the human male genital tractStructure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity.Identification of novel prostate-specific antigen-binding peptides modulating its enzyme activity.Insulin-like growth factor binding proteins (IGFBPs) as potential physiological substrates for human kallikreins hK2 and hK3.The role of molecular forms of prostate-specific antigen (PSA or hK3) and of human glandular kallikrein 2 (hK2) in the diagnosis and monitoring of prostate cancer and in extra-prostatic disease.Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs).Activation and enzymatic characterization of recombinant human kallikrein 8.Enzymatic properties of human kallikrein-related peptidase 12 (KLK12).Human tissue kallikreins: a new enzymatic cascade pathway?Analysis of prostate-specific antigen transcripts in chimpanzees, cynomolgus monkeys, baboons, and African green monkeys.The tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers.Evolution of kallikrein-related peptidases in mammals and identification of a genetic locus encoding potential regulatory inhibitors.A Single Glycan at the 99-Loop of Human Kallikrein-related Peptidase 2 Regulates Activation and Enzymatic Activity.The kallikrein world: an update on the human tissue kallikreins.New insights into the functional mechanisms and clinical applications of the kallikrein-related peptidase family.Functional intersection of the kallikrein-related peptidases (KLKs) and thrombostasis axis.Kallikrein-related peptidases (KLKs) as emerging therapeutic targets: focus on prostate cancer and skin pathologies.A functional variant in miR-143 promoter contributes to prostate cancer risk.Inhibitors of kallikrein-related peptidases: An overview.Inhibition profiles of human tissue kallikreins by serine protease inhibitors.Production and activation of recombinant hK2 with propeptide mutations resulting in high expression levels.Birth-and-death of KLK3 and KLK2 in primates: evolution driven by reproductive biology.Activation of latent protease function of pro-hK2, but not pro-PSA, involves autoprocessing.Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins
P2860
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P2860
Enzymatic action of human glandular kallikrein 2 (hK2). Substrate specificity and regulation by Zn2+ and extracellular protease inhibitors
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Enzymatic action of human glan ...... racellular protease inhibitors
@ast
Enzymatic action of human glan ...... racellular protease inhibitors
@en
Enzymatic action of human glan ...... racellular protease inhibitors
@nl
type
label
Enzymatic action of human glan ...... racellular protease inhibitors
@ast
Enzymatic action of human glan ...... racellular protease inhibitors
@en
Enzymatic action of human glan ...... racellular protease inhibitors
@nl
prefLabel
Enzymatic action of human glan ...... racellular protease inhibitors
@ast
Enzymatic action of human glan ...... racellular protease inhibitors
@en
Enzymatic action of human glan ...... racellular protease inhibitors
@nl
P2093
P2860
P1433
P1476
Enzymatic action of human glan ...... racellular protease inhibitors
@en
P2093
P2860
P356
10.1046/J.1432-1327.1999.00433.X
P407
P577
1999-06-01T00:00:00Z