The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
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Pharmacogenetics of drug-metabolizing enzymes: implications for a safer and more effective drug therapyThe zebrafish progranulin gene family and antisense transcripts.Intergenic mRNA molecules resulting from trans-splicingThe persistent contributions of RNA to eukaryotic gen(om)e architecture and cellular functionGenetic variability in CYP3A5 and its possible consequences.Identification and analysis of pig chimeric mRNAs using RNA sequencing dataThe frameshift polymorphism CYP3A43_74_delA is associated with poor differentiation of breast tumors.Origin and evolution of a chimeric fusion gene in Drosophila subobscura, D. madeirensis and D. guanche.Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.Review article: breath testing for human liver function assessment.Construction of mate pair full-length cDNAs libraries and characterization of transcriptional start sites and termination sites.Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing.Cytochrome P450 3A polymorphisms and immunosuppressive drugs.Antimycotic drug discovery in the age of genomics.Tracking the shift to 'postgenomics'.Alternative splicing within the human cytochrome P450 superfamily with an emphasis on the brain: The convolution continues.Clinical implications of CYP3A polymorphisms.Cytochrome P450 3A polymorphisms and immunosuppressive drugs: an update.Molecular population genetics of human CYP3A locus: signatures of positive selection and implications for evolutionary environmental medicine.The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy.Long-term virus-induced alterations of CYP3A-mediated drug metabolism: a look at the virology, immunology and molecular biology of a multi-faceted problem.Using drug probes to monitor hepatic drug metabolism in critically ill patients: midazolam, a flawed but useful tool for clinical investigation of CYP3A activity?Overview of pharmacogenetics.Developmental changes in the expression and function of cytochrome P450 3A isoforms: evidence from in vitro and in vivo investigations.Detection and analysis of spliced chimeric mRNAs in sequence databanks.CYP3AP1*3 allele is associated with lipid-lowering efficacy of simvastatin and atorvastatin in Chinese women.Acute kidney injury reduces the hepatic metabolism of midazolam in critically ill patients.The influence of pharmacogenetics on the time to achieve target tacrolimus concentrations after kidney transplantation.The induction of cytochrome P450 3A5 (CYP3A5) in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated receptor (CAR).A novel maturation function for clearance of the cytochrome P450 3A substrate midazolam from preterm neonates to adults.A novel polymorphic cytochrome P450 formed by splicing of CYP3A7 and the pseudogene CYP3AP1.Association of CYP3A5 polymorphisms with hypertension and antihypertensive response to verapamil.Cytotoxic doses of ketoconazole affect expression of a subset of hepatic genes.Duplication-degeneration as a mechanism of gene fission and the origin of new genes in Drosophila species.Genetic polymorphisms influence the steroid treatment of children with idiopathic nephrotic syndrome.Differential Regulation of CYP3A4 and CYP3A5 and its Implication in Drug Discovery.Ancestry-Adjusted Vitamin D Metabolite Concentrations in Association with Cytochrome 3A (CYP3A) Polymorphisms.Screening CYP3A single nucleotide polymorphisms in a Han Chinese population with a genotyping chip.Systematic screening for polymorphisms in the CYP3A4 gene in the Chinese population.
P2860
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P2860
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
@ast
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
@en
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
@nl
type
label
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
@ast
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
@en
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
@nl
prefLabel
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
@ast
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
@en
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
@nl
P1433
P1476
The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons
@en
P2093
P G Zaphiropoulos
P356
10.1016/S0378-1119(00)00470-4
P407
P577
2000-12-30T00:00:00Z