dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer
about
Linking uracil base excision repair and 5-fluorouracil toxicity in yeastRegulation of human dUTPase gene expression and p53-mediated transcriptional repression in response to oxaliplatin-induced DNA damageCrucial roles of thymidine kinase 1 and deoxyUTPase in incorporating the antineoplastic nucleosides trifluridine and 2'-deoxy-5-fluorouridine into DNA.dUTPase activity is critical to maintain genetic stability in Saccharomyces cerevisiae.New challenges and inspired answers for anticancer drug discovery and developmentPhenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistanceA prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma.Human dCTP pyrophosphatase 1 promotes breast cancer cell growth and stemness through the modulation on 5-methyl-dCTP metabolism and global hypomethylation.Application of artificial neural network to investigate the effects of 5-fluorouracil on ribonucleotides and deoxyribonucleotides in HepG2 cells.Predictive and prognostic markers in colorectal cancer.Higher expression of deoxyuridine triphosphatase (dUTPase) may predict the metastasis potential of colorectal cancerHuman and non-human primate intestinal FcRn expression and immunoglobulin G transcytosisDCTPP1 attenuates the sensitivity of human gastric cancer cells to 5-fluorouracil by up-regulating MDR1 expression epigenetically.p53 in the mitochondria, as a trans-acting protein, provides error-correction activities during the incorporation of non-canonical dUTP into DNA.Novel opportunities for thymidylate metabolism as a therapeutic target.Identification of a multi-cancer gene expression biomarker for cancer clinical outcomes using a network-based algorithm.dUTPase inhibition augments replication defects of 5-Fluorouracil.Structural model of human dUTPase in complex with a novel proteinaceous inhibitor.Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and MetabolismCysteine residues contribute to the dimerization and enzymatic activity of human nuclear dUTP nucleotidohydrolase (nDut)
P2860
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P2860
dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
dUTP nucleotidohydrolase isofo ...... orouracil in colorectal cancer
@ast
dUTP nucleotidohydrolase isofo ...... orouracil in colorectal cancer
@en
dUTP nucleotidohydrolase isofo ...... orouracil in colorectal cancer
@nl
type
label
dUTP nucleotidohydrolase isofo ...... orouracil in colorectal cancer
@ast
dUTP nucleotidohydrolase isofo ...... orouracil in colorectal cancer
@en
dUTP nucleotidohydrolase isofo ...... orouracil in colorectal cancer
@nl
prefLabel
dUTP nucleotidohydrolase isofo ...... orouracil in colorectal cancer
@ast
dUTP nucleotidohydrolase isofo ...... orouracil in colorectal cancer
@en
dUTP nucleotidohydrolase isofo ...... orouracil in colorectal cancer
@nl
P2093
P1433
P1476
dUTP nucleotidohydrolase isofo ...... orouracil in colorectal cancer
@en
P2093
J Stoehlmacher
R D Ladner
S J Caradonna
P304
P407
P577
2000-07-01T00:00:00Z