G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interaction
about
Identification of EPI64, a TBC/rabGAP domain-containing microvillar protein that binds to the first PDZ domain of EBP50 and E3KARPNHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligandsA novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptorPhosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targetsG-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosisThe scaffolding protein EBP50 regulates microvillar assembly in a phosphorylation-dependent mannerA predicted amphipathic helix mediates plasma membrane localization of GRK5A kinase-regulated mechanism controls CFTR channel gating by disrupting bivalent PDZ domain interactionsInhibition of cystic fibrosis transmembrane conductance regulator by novel interaction with the metabolic sensor AMP-activated protein kinaseRegulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factorsRole of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunityAutoinhibitory Interactions between the PDZ2 and C-terminal Domains in the Scaffolding Protein NHERF1Assembly and trafficking of a multiprotein ROMK (Kir 1.1) channel complex by PDZ interactionsG protein-coupled receptor kinase 5 regulates beta 1-adrenergic receptor association with PSD-95Regulation of GTP-binding protein alpha q (Galpha q) signaling by the ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50)Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wastingA G protein-coupled receptor kinase induces Xenopus oocyte maturationNa+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cellsThe transmembrane protein CBP plays a role in transiently anchoring small clusters of Thy-1, a GPI-anchored protein, to the cytoskeleton.NHERF: targeting and trafficking membrane proteins.Roles of ATP and cytoskeleton in the regulation of Na+/H+ exchanger along the nephron luminal membrane.Dynamics of ezrin and EBP50 in regulating microvilli on the apical aspect of epithelial cells.Signal complex regulation of renal transport proteins: NHERF and regulation of NHE3 by PKA.Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization.Cell cycle dependent association of EBP50 with protein phosphatase 2A in endothelial cellsNRFL-1, the C. elegans NHERF orthologue, interacts with amino acid transporter 6 (AAT-6) for age-dependent maintenance of AAT-6 on the membrane.Expanding the role of NHERF, a PDZ-domain containing protein adapter, to growth regulation.Roles for NHERF1 and NHERF2 on the regulation of C3a receptor signaling in human mast cellsEndosome sorting of beta 2-adrenoceptors is GRK5 independent.G protein-coupled receptor kinases: more than just kinases and not only for GPCRsSuppression of breast cancer cell growth by Na+/H+ exchanger regulatory factor 1 (NHERF1)Structural basis for NHERF1 PDZ domain bindingPlasma membrane and nuclear localization of G protein coupled receptor kinase 6A.Regulation of ion transport by the NHERF family of PDZ proteins.Phosphorylation of EBP50 negatively regulates β-PIX-dependent Rac1 activity in anoikis.NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains.G protein-coupled receptor kinase 6 acts as a critical regulator of cytokine-induced hyperalgesia by promoting phosphatidylinositol 3-kinase and inhibiting p38 signaling.Ezrin-anchored protein kinase A coordinates phosphorylation-dependent disassembly of a NHERF1 ternary complex to regulate hormone-sensitive phosphate transportArrestin scaffolds NHERF1 to the P2Y12 receptor to regulate receptor internalization.Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1
P2860
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P2860
G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interaction
description
1999 nî lūn-bûn
@nan
1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
G protein-coupled receptor kin ...... DZ domain-mediated interaction
@ast
G protein-coupled receptor kin ...... DZ domain-mediated interaction
@en
G protein-coupled receptor kin ...... DZ domain-mediated interaction
@nl
type
label
G protein-coupled receptor kin ...... DZ domain-mediated interaction
@ast
G protein-coupled receptor kin ...... DZ domain-mediated interaction
@en
G protein-coupled receptor kin ...... DZ domain-mediated interaction
@nl
prefLabel
G protein-coupled receptor kin ...... DZ domain-mediated interaction
@ast
G protein-coupled receptor kin ...... DZ domain-mediated interaction
@en
G protein-coupled receptor kin ...... DZ domain-mediated interaction
@nl
P2093
P2860
P3181
P356
P1476
G protein-coupled receptor kin ...... DZ domain-mediated interaction
@en
P2093
J A Pitcher
J T Blitzer
R F Spurney
R J Lefkowitz
P2860
P304
24328-24334
P3181
P356
10.1074/JBC.274.34.24328
P407
P577
1999-08-01T00:00:00Z