Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice
about
The sense of smell, its signalling pathways, and the dichotomy of cilia and microvilli in olfactory sensory cellsOlfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulationMolecular details of cAMP generation in mammalian cells: a tale of two systemsOlfactory Receptors in Non-Chemosensory Organs: The Nervous System in Health and DiseaseSmelling the roses and seeing the light: gene therapy for ciliopathiesOf pheromones and kairomones: what receptors mediate innate emotional responses?Odorant receptors signaling instructs the development and plasticity of the glomerular mapAdult type 3 adenylyl cyclase-deficient mice are obeseThe cell biology of smellType 3 adenylyl cyclase: a key enzyme mediating the cAMP signaling in neuronal ciliaThe type 3 adenylyl cyclase is required for the survival and maturation of newly generated granule cells in the olfactory bulbLoss of CNGB1 protein leads to olfactory dysfunction and subciliary cyclic nucleotide-gated channel trappingThe Na(+)/Ca(2+) exchanger NCKX4 governs termination and adaptation of the mammalian olfactory responseCholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptorsPhosphorylation of adenylyl cyclase III at serine1076 does not attenuate olfactory response in miceRegulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VIITranscription factor ATF5 is required for terminal differentiation and survival of olfactory sensory neuronsPhosphodiesterase 1C is dispensable for rapid response termination of olfactory sensory neuronsLoss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouseBiochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systemsCiliopathy is differentially distributed in the brain of a Bardet-Biedl syndrome mouse modelMutual influences between the main olfactory and vomeronasal systems in development and evolutionSecreted TARSH regulates olfactory mitral cell dendritic complexity.Olfactory neurons expressing transient receptor potential channel M5 (TRPM5) are involved in sensing semiochemicalsAxon fasciculation in the developing olfactory nerveVisualization of odor-induced neuronal activity by immediate early gene expression.Increases in intracellular calcium via activation of potentially multiple phospholipase C isozymes in mouse olfactory neurons.G protein-coupled odorant receptors underlie mechanosensitivity in mammalian olfactory sensory neurons.Silencing of odorant receptor genes by G protein βγ signaling ensures the expression of one odorant receptor per olfactory sensory neuron.Potential role of transient receptor potential channel M5 in sensing putative pheromones in mouse olfactory sensory neuronsOdorant-dependent generation of nitric oxide in Mammalian olfactory sensory neurons.Zicam-induced damage to mouse and human nasal tissue.Liraglutide reduces body weight by upregulation of adenylate cyclase 3.The calmodulin-stimulated adenylate cyclase ADCY8 sets the sensitivity of zebrafish retinal axons to midline repellents and is required for normal midline crossing.Topographic mapping--the olfactory system.Olfactory receptors in non-chemosensory tissues.Cilia in the CNS: the quiet organelle claims center stageAdenylyl cyclase expression and modulation of cAMP in rat taste cells.Human olfactory epithelial cells generated in vitro express diverse neuronal characteristics.Vomeronasal organ detects odorants in absence of signaling through main olfactory epithelium.
P2860
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P2860
Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice
description
2000 nî lūn-bûn
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2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Disruption of the type III ade ...... ral anosmia in transgenic mice
@ast
Disruption of the type III ade ...... ral anosmia in transgenic mice
@en
Disruption of the type III ade ...... ral anosmia in transgenic mice
@nl
type
label
Disruption of the type III ade ...... ral anosmia in transgenic mice
@ast
Disruption of the type III ade ...... ral anosmia in transgenic mice
@en
Disruption of the type III ade ...... ral anosmia in transgenic mice
@nl
prefLabel
Disruption of the type III ade ...... ral anosmia in transgenic mice
@ast
Disruption of the type III ade ...... ral anosmia in transgenic mice
@en
Disruption of the type III ade ...... ral anosmia in transgenic mice
@nl
P2093
P3181
P1433
P1476
Disruption of the type III ade ...... ral anosmia in transgenic mice
@en
P2093
P304
P3181
P356
10.1016/S0896-6273(00)00060-X
P407
P577
2000-09-01T00:00:00Z