Detection of t(4;14)(p16.3;q32) chromosomal translocation in multiple myeloma by reverse transcription-polymerase chain reaction analysis of IGH-MMSET fusion transcripts
about
Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patientsTranslocation T(4;14)(p16.3;q32) is a recurrent genetic lesion in primary amyloidosisFGF signaling inhibits the proliferation of human myeloma cells and reduces c-myc expressionGain-of-function mutation of chromatin regulators as a tumorigenic mechanism and an opportunity for therapeutic interventionIdentification of translocation products but not K-RAS mutations in memory B cells from patients with multiple myeloma.The t(14;20) is a poor prognostic factor in myeloma but is associated with long-term stable disease in monoclonal gammopathies of undetermined significanceThree-dimensional genome architecture influences partner selection for chromosomal translocations in human disease.MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signalingGlobal chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia.TACC3 is essential for EGF-mediated EMT in cervical cancerSevere short stature and Wolf-Hirschhorn syndrome: response to growth hormone in two cases without growth hormone deficiencyMicrofluidic chips for detecting the t(4;14) translocation and monitoring disease during treatment using reverse transcriptase-polymerase chain reaction analysis of IgH-MMSET hybrid transcriptsThe multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity.The translocation t(4;14) can be present only in minor subclones in multiple myelomaCritical signal transduction pathways in CLL.Epigenetic modifications in pediatric acute lymphoblastic leukemia.MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells.MB4-2/MB4-3 transcripts of IGH-MMSET fusion gene in t(4;14)pos multiple myeloma indicate poor prognosis.Fibroblast growth factor signaling and inhibition in non-small cell lung cancer and their role in squamous cell tumors.
P2860
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P2860
Detection of t(4;14)(p16.3;q32) chromosomal translocation in multiple myeloma by reverse transcription-polymerase chain reaction analysis of IGH-MMSET fusion transcripts
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
@zh-mo
2000年論文
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2000年论文
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name
Detection of t(4;14)(p16.3;q32 ...... f IGH-MMSET fusion transcripts
@ast
Detection of t(4;14)(p16.3;q32 ...... f IGH-MMSET fusion transcripts
@en
Detection of t(4;14)(p16.3;q32 ...... f IGH-MMSET fusion transcripts
@nl
type
label
Detection of t(4;14)(p16.3;q32 ...... f IGH-MMSET fusion transcripts
@ast
Detection of t(4;14)(p16.3;q32 ...... f IGH-MMSET fusion transcripts
@en
Detection of t(4;14)(p16.3;q32 ...... f IGH-MMSET fusion transcripts
@nl
prefLabel
Detection of t(4;14)(p16.3;q32 ...... f IGH-MMSET fusion transcripts
@ast
Detection of t(4;14)(p16.3;q32 ...... f IGH-MMSET fusion transcripts
@en
Detection of t(4;14)(p16.3;q32 ...... f IGH-MMSET fusion transcripts
@nl
P2093
P1433
P1476
Detection of t(4;14)(p16.3;q32 ...... f IGH-MMSET fusion transcripts
@en
P2093
Compasso S
Lombardi L
Perfetti V
P304
P407
P50
P577
2000-08-01T00:00:00Z