Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
about
The inhibitor ABIN-2 disrupts the interaction of receptor-interacting protein with the kinase subunit IKKgamma to block activation of the transcription factor NF-kappaB and potentiate apoptosisRole of Tax protein in human T-cell leukemia virus type-I leukemogenicityNEMO trimerizes through its coiled-coil C-terminal domainComplete reconstitution of human IkappaB kinase (IKK) complex in yeast. Assessment of its stoichiometry and the role of IKKgamma on the complex activity in the absence of stimulationNEMO oligomerization in the dynamic assembly of the IkappaB kinase core complexDeficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations.Structural Basis for the Activation of IKK1/αTyrosine phosphorylation is required for IkappaB kinase-beta (IKKbeta) activation and function in osteoclastogenesisStimulation of IKK-gamma oligomerization by the human T-cell leukemia virus oncoprotein Tax.Role of CXCL1 in tumorigenesis of melanoma.A structural basis for IκB kinase 2 activation via oligomerization-dependent trans auto-phosphorylationTherapeutic modulation of inflammatory gene transcription by kinase inhibitors.Polyubiquitination events mediate polymethylmethacrylate (PMMA) particle activation of NF-kappaB pathwayEvidence that the kinase-truncated c-Src regulates NF-κB signaling by targeting NEMO.A20/TNFAIP3 inhibits NF-κB activation induced by the Kaposi's sarcoma-associated herpesvirus vFLIP oncoprotein.Role of the NF-kappaB axis in immune modulation of osteoclasts and bone loss.Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell infiltration into multiple organs and improves survival period for ATL model miceA novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells.NF-kappaB in inflammatory bowel disease.The zinc finger domain of IKKγ (NEMO) protein in health and diseaseNF-κB signaling and bone resorption.Caspase control: protagonists of cancer cell apoptosis.Activity of hypoxia-inducible factor 2alpha is regulated by association with the NF-kappaB essential modulator.IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program.Novel insights into the cellular mechanisms of the anti-inflammatory effects of NF-kappaB essential modulator binding domain peptides.Detection of IKKbeta-IKKgamma subcomplexes in monocytic cells and characterization of associated signaling.The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains.Regulation of Ikappa B kinase (IKK)gamma /NEMO function by IKKbeta -mediated phosphorylation.Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1.Characterization of the Ikappa B-kinase NEMO binding domain.Evidence for M1-Linked Polyubiquitin-Mediated Conformational Change in NEMO.Mechanism of vaccinia viral protein B14 mediated inhibition of IκB kinase β activation.High levels of cytoplasmic HTLV-1 Tax mutant proteins retain a Tax-NF-kappaB-CBP ternary complex in the cytoplasm.
P2860
Q24300971-2889A6CD-A8A2-4EC0-80FF-374CC8136761Q24802464-FC8799C6-DEBD-4B00-92B4-99D6B3753817Q28205098-0E9D4ACB-FDBD-4649-9534-B555BBC15145Q28208562-D5172421-63FD-492F-A849-F5021FDA3D7BQ28584007-7B655ACB-8095-47C7-8637-66003DDAEA98Q30453097-B36FBB06-64E4-486C-BB6F-1F27BCCFC35BQ33900720-BCB57F5D-DEB3-4AB2-B9A0-CE997C178C40Q34055858-640D15A8-BDC9-48A8-B953-1E6217F8B4B5Q34159321-B6BD373B-CCA5-44E6-B146-163B10D9842EQ34724089-1E898CD9-0A48-4BEF-969F-531EBA4EE917Q34775516-B6DD1919-D25A-4821-8849-9CEEB58202D4Q34779788-CA22F354-7DDE-4480-8D4E-840F296AF563Q35084995-177304F7-1F99-4C9F-9960-55F289D83CBEQ35860261-346ED0B8-74E2-4907-B498-FE7453075795Q36673788-7DD56B96-E18B-4D9E-8B2D-C61DD4D028D8Q37118770-1D72E2D0-5DA6-4FAE-9143-40DE9F607369Q37148106-3F9714A4-8659-40B8-8842-A76779938D3DQ37156703-B073F319-9530-43EC-8121-57729E739A59Q37163422-F1E922A6-F431-4B1E-9B4F-D729FFDD7C13Q37295365-3C5CA5CF-C7A3-45F7-8285-FC3F4AF742DEQ37449635-F5058641-8D08-4EC9-AE03-1669CA60A209Q38052382-0CD1FF40-96F9-4DAF-A8AE-38A7BD48D5EBQ38331952-0BAC5996-5D1E-48EA-9D7D-D94152E84361Q38363101-E8F8868C-6149-4922-915E-00F75D06F14EQ40186974-404134BD-2543-443A-BF6E-A6D7A935B621Q40540380-245FB3B8-D322-48AF-93D2-6FDCA0A6FE76Q40563272-EF0E08FC-501F-40CA-89B8-F79BEBB2EB59Q40736146-13A41A44-1BEA-4651-8D2A-0F1F18A993BFQ41982733-AB161241-88BE-4516-879F-F4C10B372CC8Q44147137-99091D08-7583-401D-A4CD-5399704D8F35Q47431945-2DA5CBFA-D337-488C-BB22-C7DDD8EBD905Q54110809-AE237F48-75B1-43D9-8805-AF37BC96DEB6Q55239504-12E8AF1B-E6DD-473D-8606-5FB75266F902
P2860
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
@ast
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
@en
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
@nl
type
label
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
@ast
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
@en
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
@nl
prefLabel
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
@ast
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
@en
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
@nl
P2093
P2860
P356
P1476
Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex
@en
P2093
P2860
P304
P356
10.1074/JBC.M008353200
P407
P577
2001-02-09T00:00:00Z