Purification and characterization of recombinant, human acid ceramidase. Catalytic reactions and interactions with acid sphingomyelinase
about
Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomesCeramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphateEvaluation of the role of secretory sphingomyelinase and bioactive sphingolipids as biomarkers in hemophagocytic lymphohistiocytosisA catalytic mechanism for cysteine N-terminal nucleophile hydrolases, as revealed by free energy simulationsOverexpression and mass spectrometry analysis of mature human acid ceramidase.Deregulation of sphingolipid metabolism in Alzheimer's disease.Gaucher's disease and cancer: a sphingolipid perspectiveA novel mechanism of lysosomal acid sphingomyelinase maturation: requirement for carboxyl-terminal proteolytic processing.Acid sphingomyelinase deficiency attenuates bleomycin-induced lung inflammation and fibrosis in mice.Acid ceramidase maintains the chondrogenic phenotype of expanded primary chondrocytes and improves the chondrogenic differentiation of bone marrow-derived mesenchymal stem cellsRegulation of CC ligand 5/RANTES by acid sphingomyelinase and acid ceramidase.Identification of cystatin SA as a novel inhibitor of acid ceramidase.Acid ceramidase improves the quality of oocytes and embryos and the outcome of in vitro fertilization.Acid Sphingomyelinase Mediates Oxidized-LDL Induced Apoptosis in Macrophage via Endoplasmic Reticulum Stress.Acid ceramidase treatment enhances the outcome of autologous chondrocyte implantation in a rat osteochondral defect model.In vivo delivery of human acid ceramidase via cord blood transplantation and direct injection of lentivirus as novel treatment approaches for Farber disease.The vascular S1P gradient-cellular sources and biological significance.Construction of conditional acid ceramidase knockout mice and in vivo effects on oocyte development and fertility.Molecular targeting of acid ceramidase: implications to cancer therapy.Ceramide in bacterial infections and cystic fibrosis.Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice.Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases.The role of sphingolipids in respiratory disease.Global Membrane Protein Interactome Analysis using In vivo Crosslinking and Mass Spectrometry-based Protein Correlation Profiling.Ceramide formation mediated by acid sphingomyelinase facilitates endosomal escape of caliciviruses.Increased acid ceramidase expression depends on upregulation of androgen-dependent deubiquitinases, USP2, in a human prostate cancer cell line, LNCaP.Autoproteolytic cleavage and activation of human acid ceramidase.Regulation of the sphingosine-recycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function.Human acid sphingomyelinase structures provide insight to molecular basis of Niemann-Pick disease.Protein kinase C-δ isoform mediates lysosome labilization in DNA damage-induced apoptosisExtracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient.Sphingolipids in the lungs.Molecular Targeting of Acid Ceramidase in Glioblastoma: A Review of Its Role, Potential Treatment, and Challenges.
P2860
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P2860
Purification and characterization of recombinant, human acid ceramidase. Catalytic reactions and interactions with acid sphingomyelinase
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Purification and characterizat ...... ons with acid sphingomyelinase
@ast
Purification and characterizat ...... ons with acid sphingomyelinase
@en
Purification and characterizat ...... ons with acid sphingomyelinase
@nl
type
label
Purification and characterizat ...... ons with acid sphingomyelinase
@ast
Purification and characterizat ...... ons with acid sphingomyelinase
@en
Purification and characterizat ...... ons with acid sphingomyelinase
@nl
prefLabel
Purification and characterizat ...... ons with acid sphingomyelinase
@ast
Purification and characterizat ...... ons with acid sphingomyelinase
@en
Purification and characterizat ...... ons with acid sphingomyelinase
@nl
P2093
P2860
P3181
P356
P1476
Purification and characterizat ...... ons with acid sphingomyelinase
@en
P2093
Arie Dagan
Edward H Schuchman
Heike Schulze
Konrad Sandhoff
Nozomu Okino
Rajwinder Dhami
Shimon Gatt
Xingxuan He
P2860
P304
P3181
P356
10.1074/JBC.M301936200
P407
P577
2003-08-29T00:00:00Z