Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel
about
The TRPM7 chanzyme is cleaved to release a chromatin-modifying kinaseFunctional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7A novel alpha kinase EhAK1 phosphorylates actin and regulates phagocytosis in Entamoeba histolyticaCrystal Structure of the -Kinase Domain of Dictyostelium Myosin Heavy Chain Kinase ADifferential regulation of transient receptor potential melastatin 6 and 7 cation channels by ANG II in vascular smooth muscle cells from spontaneously hypertensive ratsTRPM7, a novel regulator of actomyosin contractility and cell adhesion.Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasionTRPM7Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in women.Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders.Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channelsMethionine sulfoxide reductase B1 (MsrB1) recovers TRPM6 channel activity during oxidative stressTRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions.The Mg2+ and Mg(2+)-nucleotide-regulated channel-kinase TRPM7.Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer.TRPM7 is essential for Mg(2+) homeostasis in mammals.Aldosterone signaling through transient receptor potential melastatin 7 cation channel (TRPM7) and its α-kinase domainTRPM7 regulates vascular endothelial cell adhesion and tube formation.Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel ActivityNovel Alleles of gon-2, a C. elegans Ortholog of Mammalian TRPM6 and TRPM7, Obtained by Genetic Reversion Screens.TRPM7 channel is regulated by magnesium nucleotides via its kinase domain.TRPM6 and TRPM7: A Mul-TRP-PLIK-cation of channel functions.Potentiation of TRPM7 inward currents by protonsCharge screening by internal pH and polyvalent cations as a mechanism for activation, inhibition, and rundown of TRPM7/MIC channels.Remodeling of calcium signaling in tumor progression.TRPM7 is regulated by halides through its kinase domainCalcium/calmodulin-dependent phosphorylation of tumor protein D52 on serine residue 136 may be mediated by CAMK2delta6.Calciotropic and magnesiotropic TRP channels.Silencing TRPM7 promotes growth/proliferation and nitric oxide production of vascular endothelial cells via the ERK pathway.TRPM7 and TRPM8 Ion Channels in Pancreatic Adenocarcinoma: Potential Roles as Cancer Biomarkers and TargetsThe TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels.Unreported intrinsic disorder in proteins: Disorder emergency room.The alpha-kinase family: an exceptional branch on the protein kinase tree.Role of manganese in neurodegenerative diseases.TRPM7, the cytoskeleton and neuronal death.Cellular and Developmental Biology of TRPM7 Channel-Kinase: Implicated Roles in Cancer.Inherited disorders of renal hypomagnesaemia.The Transient Receptor Potential Melastatin 7 Channel Regulates Pancreatic Cancer Cell Invasion through the Hsp90α/uPA/MMP2 pathway.Constitutive calcium entry and cancer: updated views and insights.
P2860
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P2860
Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Characterization of the protei ...... receptor potential ion channel
@ast
Characterization of the protei ...... receptor potential ion channel
@en
Characterization of the protei ...... receptor potential ion channel
@nl
type
label
Characterization of the protei ...... receptor potential ion channel
@ast
Characterization of the protei ...... receptor potential ion channel
@en
Characterization of the protei ...... receptor potential ion channel
@nl
prefLabel
Characterization of the protei ...... receptor potential ion channel
@ast
Characterization of the protei ...... receptor potential ion channel
@en
Characterization of the protei ...... receptor potential ion channel
@nl
P2093
P356
P1476
Characterization of the protei ...... receptor potential ion channel
@en
P2093
Alexey G Ryazanov
Athar Ansari
Lillia V Ryazanova
Maxim V Dorovkov
P304
P356
10.1074/JBC.M308820200
P407
P577
2004-01-30T00:00:00Z