Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins - Wikidata - awgldk - TriplyDB

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

http://www.wikidata.org/entity/Q28182259

about

Enabling functional genomics with genome engineering Epigenome engineering in cancer: fairytale or a realistic path to the clinic?Chromatin regulation at the frontier of synthetic biology Heterodimeric DNA methyltransferases as a platform for creating designer zinc finger methyltransferases for targeted DNA methylation in cells.The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes.Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers.Targeted DNA methylation using an artificially bisected M.HhaI fused to zinc fingers.Writing and rewriting the epigenetic code of cancer cells: from engineered proteins to small molecules Deep sequencing of large library selections allows computational discovery of diverse sets of zinc fingers that bind common targets.Directed evolution of improved zinc finger methyltransferases.A systematic survey of the Cys2His2 zinc finger DNA-binding landscape.Sequence-specific modification of mitochondrial DNA using a chimeric zinc finger methylase Early life nutrition and neural plasticity Finding of a highly efficient ZFN pair for Aqpep gene functioning in murine zygotes Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes.Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.Potential directions for drug development for osteoarthritis.Rewriting DNA Methylation Signatures at Will: The Curable Genome Within Reach?Targeted DNA methylation in human cells using engineered dCas9-methyltransferases.Chimeric DNA methyltransferases target DNA methylation to specific DNA sequences and repress expression of target genes.An engineered split M.HhaI-zinc finger fusion lacks the intended methyltransferase specificity.Genome engineering: a new approach to gene therapy for neuromuscular disorders.A directed evolution design of a GCG-specific DNA hemimethylase.Heritable gene repression through the action of a directed DNA methyltransferase at a chromosomal locus.Specific targeting of cytosine methylation to DNA sequences in vivo.Genome-wide DNA methylation patterns of bovine blastocysts derived from in vivo embryos subjected to in vitro culture before, during or after embryonic genome activation.

P2860

Q26782747-10E39864-FA92-4639-A187-798A716F9D16 Q26861350-C95D057C-D881-4490-A0A8-EEB23A55FD56 Q28083608-04FA510E-C998-4B03-8BB7-94B34AE70B26 Q33719384-2D4555A2-EB36-4558-B821-AA8C47F27CC6 Q34180593-E7496045-61D4-4683-AA8B-C3D509F07018 Q34376497-AB7B4B4C-42E5-46D6-B382-DE2EB1E4C3B1 Q34381076-3D017796-E8E3-4073-9082-B39A01ECBC37 Q34416190-FA29C8DD-C778-47A4-BAD2-568E2F446BD6 Q34476349-E5BF16FA-C21C-415B-B80A-2DFE61FEFE1F Q35038272-E34767C6-2754-454A-8340-BB90BFA616C2 Q35165535-2C44F309-1760-4600-B649-AC93C823ADB3 Q35543671-39245FAD-2A61-4A81-997C-5AABB9E066AA Q35544425-5B0B8D96-F3A1-4063-82E2-F322CF4A414C Q35646370-D8CE82E7-9E0C-45C9-BBF0-A0F1B5241762 Q36387894-1760CC58-8BA1-4F25-9BAA-D7A285E1BF9B Q36435079-6E231AED-7A2A-4661-87D0-B0E8DE00E894 Q36585524-ADD6D52A-6563-4133-B234-3CE0D6CCD0E2 Q36742102-24FD6DDC-3C83-4D98-A21B-313C495063EC Q38088793-07E6053F-74EA-4DA4-8970-30B34D800E20 Q39003561-57E2B5CF-AA86-45F5-A1A2-CBA2BCDC00FC Q40104894-52555B57-3EFC-4C94-9EEB-4F007452F25C Q40199783-78E74598-8669-40C8-861E-4635BF575262 Q41660887-94DB0808-A801-4CB3-8A1E-5328DB63FF1A Q41928233-A5D48A90-88D7-4794-811D-8083DFA60A07 Q41958418-6FFBC977-21C7-46D4-A4F8-999E1AADA10F Q42816880-46BE09DB-BD80-478B-B166-6B6633E9740C Q42942754-6754379C-B77A-4871-99C3-6661C8E8D6F4 Q55279758-A2EA027C-D0A1-4C7A-941B-7113A4BFAFBF

P2860

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

http://www.wikidata.org/entity/Q28182259

description

2003 nî lūn-bûn

@nan

2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

@ast

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

@en

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

@nl

type

label

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

@ast

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

@en

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

@nl

prefLabel

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

@ast

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

@en

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

@nl

P1433

Q28182259-F61E9E21-63A2-4065-BDF9-B9ABB9C0AC7E

P1476

Q28182259-1BE64EC5-4BB9-493B-8645-4C01C0B3393C

P2093

Q28182259-785F498C-8DE0-4D2C-AFE6-9C0424883A3F

Q28182259-9266D227-8FCC-478F-B64E-C476CC1CB526

Q28182259-BA0615DD-9F15-4AFC-8CC9-B0E07A9F04F5

P2860

Q28182259-00DF91E6-5041-44F0-A801-8CE6D30F416F

Q28182259-0383EE7D-20AE-4497-BE08-1BDBDFF1765D

Q28182259-05495B2C-3622-4EA0-865B-F6A00A35B279

Q28182259-142216E8-8E4D-487B-B8E2-586FC43DC430

Q28182259-152A1D53-792B-49EE-B522-07DB906C1479

Q28182259-161000AC-6B42-4AA9-8D1E-38ED16AEE42F

Q28182259-1FBDC5BF-C243-4D1C-AF9D-F60055529B16

Q28182259-2A6AE115-3266-4D1F-B31E-5ADF45D25252

Q28182259-2E5F7301-D51F-427D-891B-5D9BDDC589CA

Q28182259-2ECB79A7-A702-484C-929B-80593C7E470B

P304

Q28182259-2DFE9175-62C4-4C9F-AE30-8669E990FD17

P31

Q28182259-B027E33D-DEB7-43ED-A2FF-C6F46D72D911

P356

Q28182259-689F26F7-C180-43A4-8B69-CE65E7D0F4F4

P407

Q28182259-FD847AE6-610E-4EC1-B5C7-5CEE1AA90D62

P433

Q28182259-708FA5C7-2931-484E-AEE6-7370D29BC780

P478

Q28182259-C6A13E01-E61E-4D68-B332-94F4695B575E

P577

Q28182259-3353F05A-9DF1-4DB3-A5CB-205E33C2B059

P5875

Q28182259-4EB9994E-7277-42DD-A5A2-35282F68C264

P698

Q28182259-4B0AE19C-5980-40DE-9732-1A53FA1B1140

P921

Q28182259-B10EF392-83F9-4288-8A95-17598CE9EF72

P932

Q28182259-DADC3F67-4212-49BF-B7ED-0E4ADEA0994E

P356

P1433

Nucleic Acids Research

P1476

Site-selective in vivo targeting of cytosine-5 DNA methylation by zinc-finger proteins

@en

P2093

Christopher D Carvin

http://www.w3.org/2001/XMLSchema#string

Michael P Kladde

http://www.w3.org/2001/XMLSchema#string

Rebecca D Parr

http://www.w3.org/2001/XMLSchema#string

P2860

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

DNA methylation patterns and epigenetic memory

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

High sensitivity mapping of methylated cytosines

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

Rearrangement of side-chains in a Zif268 mutant highlights the complexities of zinc finger-DNA recognition

The fundamental role of epigenetic events in cancer

Identification of in vivo DNA targets of chromatin proteins using tethered dam methyltransferase

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

P304

6493-501

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/NAR/GKG853

http://www.w3.org/2001/XMLSchema#string

P407

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

31

http://www.w3.org/2001/XMLSchema#string

P577

2003-11-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

9021644

http://www.w3.org/2001/XMLSchema#string

P698

14602907

http://www.w3.org/2001/XMLSchema#string

P921

DNA methylation

P932

275549

http://www.w3.org/2001/XMLSchema#string