Site-directed mutagenesis of serine 40 of rat tyrosine hydroxylase. Effects of dopamine and cAMP-dependent phosphorylation on enzyme activity
about
Tyrosine hydroxylase and regulation of dopamine synthesisIdentification of iron ligands in tyrosine hydroxylase by mutagenesis of conserved histidinyl residuesProtein kinase C delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2A activity in dopaminergic neuronsReduction and oxidation of the active site iron in tyrosine hydroxylase: kinetics and specificityProgesterone decreases tyrosine hydroxylase phosphorylation state and increases protein phosphatase 2A activity in the stalk-median eminence on proestrous afternoon.Serine 129 phosphorylation reduces the ability of alpha-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo.Local modulation of steroid action: rapid control of enzymatic activity.Human and quail aromatase activity is rapidly and reversibly inhibited by phosphorylating conditions.High-level expression and deletion mutagenesis of human tryptophan hydroxylaseEffects of phosphorylation by protein kinase A on binding of catecholamines to the human tyrosine hydroxylase isoforms.Kinetics of regulatory serine variants of tyrosine hydroxylase with cyclic AMP-dependent protein kinase and extracellular signal-regulated protein kinase 2.Identification of tyrosine hydroxylase as a physiological substrate for Cdk5.Effects of mutations in tyrosine hydroxylase associated with progressive dystonia on the activity and stability of the protein.Behavioral effects of brain-derived estrogens in birds.Phosphorylation state of tyrosine hydroxylase in the stalk-median eminence is decreased by progesterone in cycling female ratsComplexity of dopamine metabolism.Neurochemical characterization of tyrosine hydroxylase-immunoreactive interneurons in the developing rat cerebral cortexEvidence for developmental dopaminergic alterations in the human immunodeficiency virus-1 transgenic rat.Allosteric regulation of phenylalanine hydroxylase.Structure and function of the aromatic amino acid hydroxylases.Activation of tyrosine hydroxylase mRNA translation by cAMP in midbrain dopaminergic neurons.Mutagenesis of a specificity-determining residue in tyrosine hydroxylase establishes that the enzyme is a robust phenylalanine hydroxylase but a fragile tyrosine hydroxylaseExpression and purification of recombinant human tyrosine hydroxylase as a fusion protein in Escherichia coli.Expression and characterization of catalytic and regulatory domains of rat tyrosine hydroxylaseDeletion mutants of tyrosine hydroxylase identify a region critical for heparin binding.Identification by hydrogen/deuterium exchange of structural changes in tyrosine hydroxylase associated with regulation.L-Tyrosine availability affects basal and stimulated catecholamine indices in prefrontal cortex and striatum of the rat.
P2860
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P2860
Site-directed mutagenesis of serine 40 of rat tyrosine hydroxylase. Effects of dopamine and cAMP-dependent phosphorylation on enzyme activity
description
1992 nî lūn-bûn
@nan
1992 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Site-directed mutagenesis of s ...... phorylation on enzyme activity
@ast
Site-directed mutagenesis of s ...... phorylation on enzyme activity
@en
Site-directed mutagenesis of s ...... phorylation on enzyme activity
@nl
type
label
Site-directed mutagenesis of s ...... phorylation on enzyme activity
@ast
Site-directed mutagenesis of s ...... phorylation on enzyme activity
@en
Site-directed mutagenesis of s ...... phorylation on enzyme activity
@nl
prefLabel
Site-directed mutagenesis of s ...... phorylation on enzyme activity
@ast
Site-directed mutagenesis of s ...... phorylation on enzyme activity
@en
Site-directed mutagenesis of s ...... phorylation on enzyme activity
@nl
P2093
P1476
Site-directed mutagenesis of s ...... phorylation on enzyme activity
@en
P2093
C Lauriano
J W Haycock
P F Fitzpatrick
S C Daubner
P304
P407
P577
1992-06-25T00:00:00Z