Activation of signal transducer and activator of transcription 3 by oncogenic RET/PTC (rearranged in transformation/papillary thyroid carcinoma) tyrosine kinase: roles in specific gene regulation and cellular transformation

Activation of signal transducer and activator of transcription 3 by oncogenic RET/PTC (rearranged in transformation/papillary thyroid carcinoma) tyrosine kinase: roles in specific gene regulation and cellular transformation

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http://www.wikidata.org/entity/Q28183305

Q28183305

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AZD1480 blocks growth and tumorigenesis of RET- activated thyroid cancer cell lines Stimulation of hTAFII68 (NTD)-mediated transactivation by v-Src STAT3 negatively regulates thyroid tumorigenesis Role of STAT3 in cancer metastasis and translational advances.Modulatory role of phospholipase D in the activation of signal transducer and activator of transcription (STAT)-3 by thyroid oncogenic kinase RET/PTC Role of STAT3 in in vitro transformation triggered by TRK oncogenes.Aberrant sonic hedgehog signaling pathway and STAT3 activation in papillary thyroid cancer.Down-regulation of microRNA-21 is involved in the propofol-induced neurotoxicity observed in human stem cell-derived neurons Upregulation of the signal transducers and activators of transcription 3 (STAT3) pathway in lymphatic metastases of papillary thyroid cancer Intracellular signal transduction and modification of the tumor microenvironment induced by RET/PTCs in papillary thyroid carcinoma.Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.Thyroid-specific ablation of the Carney complex gene, PRKAR1A, results in hyperthyroidism and follicular thyroid cancer.Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases.Linear combinations of docking affinities explain quantitative differences in RTK signaling The Role of STAT3 in Thyroid Cancer.The insulin resistance Grb14 adaptor protein promotes thyroid cancer ret signaling and progression.The RET oncogene in papillary thyroid carcinoma.STAT3 targeting by polyphenols: Novel therapeutic strategy for melanoma.ret/PTC-1 expression alters the immunoprofile of thyroid follicular cells Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis.Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation.Oncogenes, mitochondrial metabolism, and quality control in differentiated thyroid cancer.KIF5B-RET fusion kinase promotes cell growth by multilevel activation of STAT3 in lung cancer.Upregulation of RSPO2-GPR48/LGR4 signaling in papillary thyroid carcinoma contributes to tumor progression.Rapamycin inhibits both motility through down-regulation of p-STAT3 (S727) by disrupting the mTORC2 assembly and peritoneal dissemination in sarcomatoid cholangiocarcinoma.The management of thyroid nodules and cancer in the molecular era

P2860

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P2860

Activation of signal transducer and activator of transcription 3 by oncogenic RET/PTC (rearranged in transformation/papillary thyroid carcinoma) tyrosine kinase: roles in specific gene regulation and cellular transformation

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http://www.wikidata.org/entity/Q28183305

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2003 nî lūn-bûn

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2003 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2003 թվականի հունիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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